Overview

  • Product name

    Fluvoxamine maleate, Serotonin reuptake inhibitor (SSRI)
  • Description

    Potent, selective serotonin reuptake inhibitor (SSRI)
  • Biological description

    Potent, selective serotonin reuptake inhibitor (SSRI) (Ki = 84 nM). Agonist activity at the σ1 receptors. Antidepressant and anxiolytic effects in vivo.
  • Purity

    > 99%
  • CAS Number

    61718-82-9
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Villard V  et al. Pharmacological interaction with the sigma1 (s1)-receptor in the acute behavioral effects of antidepressants. J Pharmacol Sci 115:279-92 (2011). Read more (PubMed: 21427517) »
  • Ago Y  et al. Fluvoxamine enhances prefrontal dopaminergic neurotransmission in adrenalectomized/castrated mice via both 5-HT reuptake inhibition and s(1) receptor activation. Psychopharmacology (Berl) 217:377-86 (2011). Read more (PubMed: 21487652) »
  • Owens MJ  et al. Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites. J Pharmacol Exp Ther 283:1305-22 (1997). Read more (PubMed: 9400006) »
  • Claassen V  et al. Fluvoxamine, a specific 5-hydroxytryptamine uptake inhibitor. Br J Pharmacol 60:505-16 (1977). Read more (PubMed: 302726) »

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