Key features and details
- Rabbit polyclonal to FNIP2
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-FNIP2 antibody
DescriptionRabbit polyclonal to FNIP2
Specificityab106611 is predicted to not cross-react with FNIP1.
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Mouse, Rat, Human
Synthetic peptide corresponding to 16 amino acids near the C terminal end of Human FNIP2 (NP_065891).
- Rat skeletal muscle lysate Mouse skeletal muscle tissue
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at 4°C (stable for up to 12 months).
Storage bufferpH: 7.2
Preservative: 0.02% Sodium azide
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab106611 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use a concentration of 5 µg/ml.|
|WB||Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 122 kDa.|
FunctionMay play a role in the signal transduction pathway of apoptosis induced by O6-methylguanine-mispaired lesions (By similarity). May be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways. May regulate phosphorylation of RPS6KB1.
Tissue specificityWidely expressed with highest levels in muscle, nasal mucosa, salivary gland, uvula, fat, liver, heart, placenty and pancreas. Moderately expressed in the lung, small intestine, kidney and brain. Lower levels detected in renal cell carcinoma than in normal kidney tissue. Higher levels detected in oncocytoma than in normal kidney.
Sequence similaritiesBelongs to the FNIP family.
modificationsPhosphorylated by AMPK.
Cellular localizationCytoplasm. Co-localizes with FLCN in the cytoplasm.
- Information by UniProt
- FNIP1-like protein antibody
- Fnip2 antibody
- FNIP2_HUMAN antibody
Lane 1 : Anti-FNIP2 antibody (ab106611) at 1 µg/ml
Lane 2 : Anti-FNIP2 antibody (ab106611) at 2 µg/ml
All lanes : Rat skeletal muscle lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 122 kDa
ab106611, at 5µg/ml, staining FNIP2 in paraffin embedded Mouse skeletal muscle tissue by Immunohistochemistry.
ab106611 has been referenced in 1 publication.
- Dong R et al. IGF-1/IGF-1R blockade ameliorates diabetic kidney disease through normalizing Snail1 expression in a mouse model. Am J Physiol Endocrinol Metab 317:E686-E698 (2019). PubMed: 31361542