• Product name

    Anti-FNTA antibody - C-terminal
    See all FNTA primary antibodies
  • Description

    Rabbit polyclonal to FNTA - C-terminal
  • Host species

  • Tested applications

    Suitable for: WB, IPmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Rhesus monkey, Gorilla, Common marmoset
  • Immunogen

    Synthetic peptide within Human FNTA aa 329-379 (C terminal). The exact sequence is proprietary. NP_002018.1.


    Database link: P49354

  • Positive control

    • HeLa, 293T and Jurkat whole cell lysates.


  • Form

  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.09% Sodium azide
    Constituent: 99% Tris citrate/phosphate

    pH 7 to 8
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Purification notes

    ab186136 was affinity purified using an epitope specific to FNTA immobilized on a solid support.
  • Clonality

  • Isotype

  • Research areas


Our Abpromise guarantee covers the use of ab186136 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/2000 - 1/10000. Predicted molecular weight: 44 kDa.
IP Use at 2-10 µg/mg of lysate.


  • Function

    Catalyzes the transfer of a farnesyl or geranyl-geranyl moiety from farnesyl or geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. The alpha subunit is thought to participate in a stable complex with the substrate. The beta subunit binds the peptide substrate. Through RAC1 prenylation and activation may positively regulate neuromuscular junction development downstream of MUSK.
  • Sequence similarities

    Belongs to the protein prenyltransferase subunit alpha family.
    Contains 5 PFTA repeats.
  • Post-translational

    Phosphorylated. Phosphorylation is mediated by MUSK upon AGRIN stimulation and results in the activation of FNTA.
  • Information by UniProt
  • Database links

  • Alternative names

    • CAAX farnesyltransferase alpha subunit antibody
    • CAAX farnesyltransferase subunit alpha antibody
    • EC antibody
    • EC antibody
    • Farnesyl protein transferase alpha subunit antibody
    • Farnesyltransferase CAAX box alpha antibody
    • Farnesyltransferase, CAAX box, alpha antibody
    • Fnta antibody
    • FNTA_HUMAN antibody
    • FPTA antibody
    • FTase alpha antibody
    • FTase-alpha antibody
    • GGTase I alpha antibody
    • GGTase-I-alpha antibody
    • MGC99680 antibody
    • OTTHUMP00000229206 antibody
    • OTTHUMP00000229262 antibody
    • PGGT1A antibody
    • Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit antibody
    • Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha antibody
    • Protein prenyltransferase alpha subunit repeat containing 2 antibody
    • PTAR2 antibody
    • Ras proteins prenyltransferase alpha antibody
    • Ras proteins prenyltransferase subunit alpha antibody
    • Type I protein geranyl geranyltransferase alpha subunit antibody
    • Type I protein geranyl-geranyltransferase subunit alpha antibody
    see all


  • Detection of FNTA in Immunoprecipitates of 293T whole cell lysates (1 mg for IP, 20% of IP loaded) using ab186136 at 6 µg per reaction for IP (Lane 1). For WB detection, ab186136 was used at 1µg/ml. Lane 2 Control IgG IP. Detection: Chemiluminescence with an exposure time of 30 seconds.

  • All lanes : Anti-FNTA antibody - C-terminal (ab186136) at 0.1 µg/ml

    Lane 1 : HeLa whole cell lysate
    Lane 2 : 293T whole cell lysate
    Lane 3 : Jurkat whole cell lysate

    Lysates/proteins at 50 µg per lane.

    Developed using the ECL technique.

    Predicted band size: 44 kDa

    Exposure time: 3 minutes


This product has been referenced in:

  • Mohammad G  et al. Functional Regulation of an Oxidative Stress Mediator, Rac1, in Diabetic Retinopathy. Mol Neurobiol 56:8643-8655 (2019). Read more (PubMed: 31300985) »
See 1 Publication for this product

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