• Product name

    Anti-FNTA antibody [EPR4704]
    See all FNTA primary antibodies
  • Description

    Rabbit monoclonal [EPR4704] to FNTA
  • Host species

  • Tested applications

    Suitable for: WB, IHC-P, Flow Cytmore details
    Unsuitable for: ICC or IP
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human FNTA aa 50-150. The exact sequence is proprietary.

  • Positive control

    • Jurkat, HeLa, JAR, C6, RAW264.7, PC12, and NIH3T3 cell lysates.
  • General notes



    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.



Our Abpromise guarantee covers the use of ab109738 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 44 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval via the pressure cooker method before commencing with IHC staining protocol. Antigen retrieval recommended; heat up to 98 degrees C, below boiling, and then let cool for 10-20 min.
Flow Cyt 1/10 - 1/100.

ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.


  • Application notes
    Is unsuitable for ICC or IP.
  • Target

    • Function

      Catalyzes the transfer of a farnesyl or geranyl-geranyl moiety from farnesyl or geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. The alpha subunit is thought to participate in a stable complex with the substrate. The beta subunit binds the peptide substrate. Through RAC1 prenylation and activation may positively regulate neuromuscular junction development downstream of MUSK.
    • Sequence similarities

      Belongs to the protein prenyltransferase subunit alpha family.
      Contains 5 PFTA repeats.
    • Post-translational

      Phosphorylated. Phosphorylation is mediated by MUSK upon AGRIN stimulation and results in the activation of FNTA.
    • Information by UniProt
    • Database links

    • Alternative names

      • CAAX farnesyltransferase alpha subunit antibody
      • CAAX farnesyltransferase subunit alpha antibody
      • EC antibody
      • EC antibody
      • Farnesyl protein transferase alpha subunit antibody
      • Farnesyltransferase CAAX box alpha antibody
      • Farnesyltransferase, CAAX box, alpha antibody
      • Fnta antibody
      • FNTA_HUMAN antibody
      • FPTA antibody
      • FTase alpha antibody
      • FTase-alpha antibody
      • GGTase I alpha antibody
      • GGTase-I-alpha antibody
      • MGC99680 antibody
      • OTTHUMP00000229206 antibody
      • OTTHUMP00000229262 antibody
      • PGGT1A antibody
      • Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit antibody
      • Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha antibody
      • Protein prenyltransferase alpha subunit repeat containing 2 antibody
      • PTAR2 antibody
      • Ras proteins prenyltransferase alpha antibody
      • Ras proteins prenyltransferase subunit alpha antibody
      • Type I protein geranyl geranyltransferase alpha subunit antibody
      • Type I protein geranyl-geranyltransferase subunit alpha antibody
      see all


    • All lanes : Anti-FNTA antibody [EPR4704] (ab109738) at 1/1000 dilution

      Lane 1 : Jurkat cell lysate
      Lane 2 : HeLa cell lysate
      Lane 3 : JAR cell lysate

      Lysates/proteins at 10 µg per lane.

      Predicted band size: 44 kDa

    • All lanes : Anti-FNTA antibody [EPR4704] (ab109738) at 1/1000 dilution

      Lane 1 : C6 cell lysate
      Lane 2 : RAW264.7 cell lysate
      Lane 3 : PC12 cell lysate
      Lane 4 : NIH3T3 cell lysate

      Lysates/proteins at 10 µg per lane.

      Predicted band size: 44 kDa


    This product has been referenced in:

    • Miles RR  et al. Genome-wide screen for modulation of hepatic apolipoprotein A-I (ApoA-I) secretion. J Biol Chem 288:6386-96 (2013). WB ; Human . Read more (PubMed: 23322769) »
    • Cieslik KA  et al. Aberrant differentiation of fibroblast progenitors contributes to fibrosis in the aged murine heart: role of elevated circulating insulin levels. FASEB J 27:1761-71 (2013). Read more (PubMed: 23303205) »
    See all 2 Publications for this product

    Customer reviews and Q&As


    Thank you for contacting Abcam. The antibody ab109738 maps to between amino acids********* of human FNTA (UniProt: P49354). Please let me know if you have any other questions.

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