• Product name

    Anti-Folate Binding Protein/FBP antibody (HRP)
    See all Folate Binding Protein/FBP primary antibodies
  • Description

    Goat polyclonal to Folate Binding Protein/FBP (HRP)
  • Host species

  • Conjugation

  • Specificity

    This antibody targets both purified and partially purified Folate Binding Protein/FBP from bovine milk.

  • Tested applications

    Suitable for: WB, Dot blot, ELISA, IHC-P, IHC-Fr, Immunomicroscopymore details
  • Species reactivity

    Reacts with: Cow
  • Immunogen

    Full length native protein (purified) corresponding to Cow Folate Binding Protein/FBP. (bovine milk)

  • General notes

    Previously labelled as Folate Binding Protein


  • Form

  • Storage instructions

    Shipped at 4°C. Store at +4°C.
  • Storage buffer

    pH: 7.20
    Preservative: 0.01% Gentamicin sulphate
    Constituent: PBS

    Polyethylene glycol (PEG 8000)
  • Concentration information loading...
  • Purification notes

    Purified from monospecific antiserum by delipidation, fractionation and ion exchange chromatography.
  • Clonality

  • Isotype

  • Research areas


Our Abpromise guarantee covers the use of ab20572 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Predicted molecular weight: 31 kDa.
Dot blot Use at an assay dependent dilution.
ELISA 1/2000 - 1/12000.
IHC-P 1/100 - 1/200.
IHC-Fr 1/100 - 1/200.
Immunomicroscopy Use at an assay dependent dilution.


  • Function

    Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells.
  • Tissue specificity

    Exclusively expressed in tissues of epithelial origin. Expression is increased in malignant tissues. Expressed in kidney, lung and cerebellum.
  • Involvement in disease

    Defects in FOLR1 are the cause of neurodegeneration due to cerebral folate transport deficiency (NCFTD) [MIM:613068]. NCFTD is an autosomal recessive disorder resulting from brain-specific folate deficiency early in life. Onset is apparent in late infancy with severe developmental regression, movement disturbances, epilepsy, and leukodystrophy. Note=Recognition and diagnosis of this disorder is critical because folinic acid therapy can reverse the clinical symptoms and improve brain abnormalities and function.
  • Sequence similarities

    Belongs to the folate receptor family.
  • Post-translational

    Eight disulfide bonds are present.
    The secreted form is derived from the membrane-bound form either by cleavage of the GPI anchor, or/and by proteolysis catalyzed by a metalloprotease.
  • Cellular localization

    Cell membrane. Secreted.
  • Information by UniProt
  • Database links

  • Alternative names

    • adult antibody
    • Adult folate binding protein antibody
    • Adult folate-binding protein antibody
    • FBP antibody
    • Folate Binding Protein antibody
    • Folate Receptor 1 Adult antibody
    • Folate receptor 1 antibody
    • Folate Receptor 1 Precursor antibody
    • Folate receptor adult antibody
    • Folate receptor alpha antibody
    • Folate receptor antibody
    • FOLR antibody
    • FOLR1 antibody
    • FOLR1_HUMAN antibody
    • FR alpha antibody
    • FR-alpha antibody
    • FRalpha antibody
    • KB cells FBP antibody
    • MOV18 antibody
    • Ovarian cancer associated antigen antibody
    • Ovarian tumor associated antigen antibody
    • Ovarian tumor associated antigen MOv18 antibody
    • Ovarian tumor-associated antigen MOv18 antibody
    see all


  • Immunohistochemical analysis of Human clear cell ovarian carcinoma tissue, staining Folate Binding Protein/FBP with ab20572 at 1/200 dilution.


This product has been referenced in:

  • Siu MK  et al. Paradoxical impact of two folate receptors, FRa and RFC, in ovarian cancer: effect on cell proliferation, invasion and clinical outcome. PLoS One 7:e47201 (2012). IHC-P . Read more (PubMed: 23144806) »
See 1 Publication for this product

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