Overview

  • Product name

    Anti-Follicular Dendritic Cells antibody [Ki-M4]
  • Description

    Mouse monoclonal [Ki-M4] to Follicular Dendritic Cells
  • Host species

    Mouse
  • Specificity

    ab15628 recognises dendritic reticulum cells, lining cells of lymph node sinuses, and a small fraction of monocytes. The antibody does not cross-react with epithelial and mesenchymal cells, including macrophages and other cells from bronchial and peritoneal lavages. ab15628 does not react with any circulating cell.
  • Tested applications

    Suitable for: IHC-Frmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human Follicular Dendritic Cells. Circulating immune complexes of a patient with Hodgkin's disease.

  • Epitope

    ab15628 detects an epitope within a proteoglycan localized on the cell surface.

Properties

Applications

Our Abpromise guarantee covers the use of ab15628 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr Use a concentration of 0.5 µg/ml.

Target

  • Relevance

    Follicular dendritic cells are cells that facilitate antigen recognition by B cells in follicles. This kind of dendritic cell is not bone marrow derived and is not a kind of blood cell. It is purely a resident of the follicles of secondary lymphoid organs. B cells form germinal centers around follicular dendritic cells in lymphoid organs. Dendritic cells form from monocytes, white blood cells which circulate in the body and, depending on the right signal, can turn into dendritic cells or macrophages. The monocytes in turn are formed from stem cells in the bone marrow.
  • Alternative names

    • FDC antibody
    • FDCs antibody
    • Follicular dendritic cell antibody

References

ab15628 has not yet been referenced specifically in any publications.

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