Overview

  • Product name

  • Description

    Rabbit polyclonal to FOLR2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Human
    Predicted to work with: Rhesus monkey
  • Immunogen

    Recombinant fragment within Human FOLR2 (internal sequence). The exact sequence is proprietary.
    Database link: P14207

  • Positive control

    • WB: Jurkat, Raji and NCI-H929 whole cell extracts. IHC-P: Mouse prostate tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab228643 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 29 kDa.
IHC-P 1/100 - 1/1000.

Target

  • Function

    Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells.
  • Tissue specificity

    Expressed in placenta and hematopoietic cells. Expression is increased in malignant tissues.
  • Sequence similarities

    Belongs to the folate receptor family.
  • Post-translational
    modifications

    Eight disulfide bonds are present.
    N-glycosylated.
  • Cellular localization

    Cell membrane. Secreted.
  • Information by UniProt
  • Database links

  • Alternative names

    • beta hFR antibody
    • FBP antibody
    • FBP/PL 1 antibody
    • FBP2 antibody
    • fetal/placental antibody
    • folate receptor 2 (fetal) antibody
    • Folate receptor 2 antibody
    • Folate receptor antibody
    • Folate receptor beta antibody
    • Folate receptor, fetal/placental antibody
    • Folbp 2 antibody
    • Folbp2 antibody
    • Folr2 antibody
    • FOLR2_HUMAN antibody
    • FR beta antibody
    • FR P3 antibody
    • FR-beta antibody
    • Placental folate binding protein antibody
    • Placental folate-binding protein antibody
    see all

Images

  • All lanes : Anti-FOLR2 antibody (ab228643) at 1/1000 dilution

    Lane 1 : Jurkat (human T cell leukemia cell line from peripheral blood) whole cell extract
    Lane 2 : Raji (human Burkitt's lymphoma cell line) whole cell extract
    Lane 3 : NCI-H929 whole cell extract

    Lysates/proteins at 30 µg per lane.

    Secondary
    All lanes : HRP-conjugated anti-rabbit IgG

    Predicted band size: 29 kDa



    12% SDS-PAGE gel.

  • Paraffin-embedded mouse prostate tissue stained for FOLR2 using ab228643 at 1/500 dilution in immunohistochemical analysis.

References

ab228643 has not yet been referenced specifically in any publications.

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