Overview

  • Product name

    Fosfomycin calcium, antibiotic
  • Description

    Broad spectrum antibiotic
  • Alternative names

    • Fosmicin
  • Biological description

    Broad spectrum antibiotic. Inhibits UDP-N-acetylglucosamine enolpyruval transferase to inhibit bacterial wall synthesis. Orally active.
  • Purity

    > 97%
  • CAS Number

    26016-98-8
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    Calcium (3-methyloxiran-2-yl)-dioxido-oxo-λ5-phosphane
  • Molecular weight

    176.12
  • Molecular formula

    C3H5CaO4P
  • PubChem identifier

    5702189
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in 1M HCl to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC1C(O1)P(=O)([O-])[O-].[Ca+2]
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Oliva A  et al. Activity of fosfomycin and rifampin on planktonic and adherent Enterococcus faecalis in an experimental foreign-body infection model. Antimicrob Agents Chemother : (2013). Read more (PubMed: 24145537) »
  • Kurabayashi K  et al. The role of the CpxAR two-component signal transduction system in control of fosfomycin resistance and carbon substrate uptake. J Bacteriol : (2013). Read more (PubMed: 24163343) »
  • Devriese LA  et al. A simple identification scheme for coagulase negative staphylococci from bovine mastitis. Res Vet Sci 57:240-4 (1994). Read more (PubMed: 7817013) »

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