Anti-FOXG1 antibody - ChIP Grade (ab18259)

Rabbit polyclonal FOXG1 antibody. Validated in WB, IHC, ChIP, ICC/IF and tested in Mouse, Rat, Human, Xenopus laevis. Cited in 47 publication(s). Independently reviewed in 11 review(s).

Publishing research using ab18259? Please let us know so that we can cite the reference in this datasheet.

ab18259 has been referenced in 53 publications.

  • Schafer ST  et al. Pathological priming causes developmental gene network heterochronicity in autistic subject-derived neurons. Nat Neurosci N/A:N/A (2019). IF . PubMed: 30617258
  • Peng JJ  et al. Repetitive transcranial magnetic stimulation promotes functional recovery and differentiation of human neural stem cells in rats after ischemic stroke. Exp Neurol 313:1-9 (2019). PubMed: 30529277
  • Goto-Silva L  et al. Computational fluid dynamic analysis of physical forces playing a role in brain organoid cultures in two different multiplex platforms. BMC Dev Biol 19:3 (2019). PubMed: 30841924
  • Boisvert EM  et al. Minocycline mitigates the effect of neonatal hypoxic insult on human brain organoids. Cell Death Dis 10:325 (2019). PubMed: 30975982
  • Dali R  et al. Characterization of a FOXG1:TLE1 transcriptional network in glioblastoma-initiating cells. Mol Oncol 12:775-787 (2018). PubMed: 29316219
  • Liu B  et al. Forced Expression of Foxg1 in the Cortical Hem Leads to the Transformation of Cajal-Retzius Cells into Dentate Granule Neurons. J Dev Biol 6:N/A (2018). PubMed: 29949945
  • Mattei C  et al. Generation of Neural Organoids from Human Embryonic Stem Cells Using the Rotary Cell Culture System: Effects of Microgravity on Neural Progenitor Cell Fate. Stem Cells Dev 27:848-857 (2018). PubMed: 29649415
  • Han X  et al. FoxG1 Directly Represses Dentate Granule Cell Fate During Forebrain Development. Front Cell Neurosci 12:452 (2018). PubMed: 30532694
  • Weise SC  et al. FOXG1 Regulates PRKAR2B Transcriptionally and Posttranscriptionally via miR200 in the Adult Hippocampus. Mol Neurobiol N/A:N/A (2018). PubMed: 30539330
  • Liu B  et al. Foxg1 deletion impairs the development of the epithalamus. Mol Brain 11:5 (2018). PubMed: 29394901
  • Chen J  et al. FOXG1 Expression Is Elevated in Glioma and Inhibits Glioma Cell Apoptosis. J Cancer 9:778-783 (2018). PubMed: 29581755
  • Tu J  et al. MicroRNA profiling during directed differentiation of cortical interneurons from human-induced pluripotent stem cells. FEBS Open Bio 8:502-512 (2018). PubMed: 29632804
  • Zhang M  et al. Highly efficient methods to obtain homogeneous dorsal neural progenitor cells from human and mouse embryonic stem cells and induced pluripotent stem cells. Stem Cell Res Ther 9:67 (2018). PubMed: 29544541
  • Hoffmann N  et al. DGCR8 Promotes Neural Progenitor Expansion and Represses Neurogenesis in the Mouse Embryonic Neocortex. Front Neurosci 12:281 (2018). PubMed: 29760646
  • Playne R  et al. Generation of dopamine neuronal-like cells from induced neural precursors derived from adult human cells by non-viral expression of lineage factors. J Stem Cells Regen Med 14:34-44 (2018). PubMed: 30018471
  • Bulstrode H  et al. Elevated FOXG1 and SOX2 in glioblastoma enforces neural stem cell identity through transcriptional control of cell cycle and epigenetic regulators. Genes Dev 31:757-773 (2017). PubMed: 28465359
  • Chau M  et al. Transplantation of iPS cell-derived neural progenitors overexpressing SDF-1a increases regeneration and functional recovery after ischemic stroke. Oncotarget 8:97537-97553 (2017). ICC/IF ; Human . PubMed: 29228630
  • Kimira Y  et al. Collagen-derived dipeptide prolyl-hydroxyproline promotes osteogenic differentiation through Foxg1. Cell Mol Biol Lett 22:27 (2017). PubMed: 29213293
  • Wilde JJ  et al. Diencephalic Size Is Restricted by a Novel Interplay Between GCN5 Acetyltransferase Activity and Retinoic Acid Signaling. J Neurosci 37:2565-2579 (2017). PubMed: 28154153
  • Subramanian L  et al. Dynamic behaviour of human neuroepithelial cells in the developing forebrain. Nat Commun 8:14167 (2017). IF ; Human . PubMed: 28139695
  • Bagley JA  et al. Fused cerebral organoids model interactions between brain regions. Nat Methods 14:743-751 (2017). PubMed: 28504681
  • Lancaster MA  et al. Guided self-organization and cortical plate formation in human brain organoids. Nat Biotechnol 35:659-666 (2017). PubMed: 28562594
  • Espuny-Camacho I  et al. Hallmarks of Alzheimer's Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain. Neuron 93:1066-1081.e8 (2017). PubMed: 28238547
  • Close JL  et al. Single-Cell Profiling of an In Vitro Model of Human Interneuron Development Reveals Temporal Dynamics of Cell Type Production and Maturation. Neuron 93:1035-1048.e5 (2017). PubMed: 28279351
  • Quadrato G  et al. Cell diversity and network dynamics in photosensitive human brain organoids. Nature 545:48-53 (2017). PubMed: 28445462
  • Toda T  et al. Nup153 Interacts with Sox2 to Enable Bimodal Gene Regulation and Maintenance of Neural Progenitor Cells. Cell Stem Cell 21:618-634.e7 (2017). PubMed: 28919367
  • Xu CC  et al. Abnormal mitochondrial transport and morphology as early pathological changes in human models of spinal muscular atrophy. Dis Model Mech 9:39-49 (2016). Human . PubMed: 26586529
  • Frullanti E  et al. Altered expression of neuropeptides in FoxG1-null heterozygous mutant mice. Eur J Hum Genet 24:252-7 (2016). PubMed: 25966633
  • Xu JC  et al. Cultured networks of excitatory projection neurons and inhibitory interneurons for studying human cortical neurotoxicity. Sci Transl Med 8:333ra48 (2016). PubMed: 27053772
  • Chen L  et al. Growth and metastasis of lung adenocarcinoma is potentiated by BMP4-mediated immunosuppression. Oncoimmunology 5:e1234570 (2016). PubMed: 27999749
  • Guye P  et al. Genetically engineering self-organization of human pluripotent stem cells into a liver bud-like tissue using Gata6. Nat Commun 7:10243 (2016). IF ; Human . PubMed: 26732624
  • Zemke M  et al. Loss of Ezh2 promotes a midbrain-to-forebrain identity switch by direct gene derepression and Wnt-dependent regulation. BMC Biol 13:103 (2015). PubMed: 26621269
  • Pancrazi L  et al. Foxg1 localizes to mitochondria and coordinates cell differentiation and bioenergetics. Proc Natl Acad Sci U S A 112:13910-5 (2015). PubMed: 26508630
  • Werner A  et al. Cell-fate determination by ubiquitin-dependent regulation of translation. Nature 525:523-7 (2015). PubMed: 26399832
  • Baek ST  et al. An AKT3-FOXG1-reelin network underlies defective migration in human focal malformations of cortical development. Nat Med 21:1445-54 (2015). IHC, ChIP . PubMed: 26523971
  • Reeh KA  et al. Ectopic TBX1 suppresses thymic epithelial cell differentiation and proliferation during thymus organogenesis. Development 141:2950-8 (2014). IHC-P ; Mouse . PubMed: 25053428
  • Kindberg AA  et al. An in vitro model of human neocortical development using pluripotent stem cells: cocaine-induced cytoarchitectural alterations. Dis Model Mech 7:1397-405 (2014). ICC/IF ; Human . PubMed: 25288682
  • Goubau C  et al. Platelet defects in congenital variant of Rett syndrome patients with FOXG1 mutations or reduced expression due to a position effect at 14q12. Eur J Hum Genet N/A:N/A (2013). Human . PubMed: 23632790
  • Weick JP  et al. Deficits in human trisomy 21 iPSCs and neurons. Proc Natl Acad Sci U S A 110:9962-7 (2013). PubMed: 23716668
  • Li JV  et al. Transcriptional repression of AIB1 by FoxG1 leads to apoptosis in breast cancer cells. Mol Endocrinol 27:1113-27 (2013). PubMed: 23660594
  • Lancaster MA  et al. Cerebral organoids model human brain development and microcephaly. Nature 501:373-9 (2013). PubMed: 23995685
  • Verginelli F  et al. Transcription factors FOXG1 and Groucho/TLE promote glioblastoma growth. Nat Commun 4:2956 (2013). PubMed: 24356439
  • Liu Y  et al. Directed differentiation of forebrain GABA interneurons from human pluripotent stem cells. Nat Protoc 8:1670-9 (2013). ICC . PubMed: 23928500
  • Sturm D  et al. Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma. Cancer Cell 22:425-37 (2012). PubMed: 23079654
  • Tian C  et al. Foxg1 has an essential role in postnatal development of the dentate gyrus. J Neurosci 32:2931-49 (2012). IHC-FoFr, WB ; Mouse . PubMed: 22378868
  • Fotaki V  et al. Wnt/ß-catenin signaling is disrupted in the extra-toes (Gli3(Xt/Xt) ) mutant from early stages of forebrain development, concomitant with anterior neural plate patterning defects. J Comp Neurol 519:1640-57 (2011). PubMed: 21452227
  • Wei Q & Condie BG A focused in situ hybridization screen identifies candidate transcriptional regulators of thymic epithelial cell development and function. PLoS One 6:e26795 (2011). PubMed: 22087235
  • Fasano CA  et al. Bmi-1 cooperates with Foxg1 to maintain neural stem cell self-renewal in the forebrain. Genes Dev 23:561-74 (2009). WB . PubMed: 19270157
  • Danesin C  et al. Integration of telencephalic Wnt and hedgehog signaling center activities by Foxg1. Dev Cell 16:576-87 (2009). ChIP ; Zebrafish . PubMed: 19386266
  • Chan DW  et al. Overexpression of FOXG1 contributes to TGF-beta resistance through inhibition of p21WAF1/CIP1 expression in ovarian cancer. Br J Cancer 101:1433-43 (2009). WB, IHC ; Human . PubMed: 19755996
  • Friedrichs M  et al. Lamination of the cerebral cortex is disturbed in Gli3 mutant mice. Dev Biol 318:203-14 (2008). PubMed: 18448089
  • Wu H  et al. Integrative genomic and functional analyses reveal neuronal subtype differentiation bias in human embryonic stem cell lines. Proc Natl Acad Sci U S A 104:13821-6 (2007). PubMed: 17693548
  • Regad T  et al. The neural progenitor-specifying activity of FoxG1 is antagonistically regulated by CKI and FGF. Nat Cell Biol 9:531-40 (2007). IHC-P, IHC-Fr ; Mouse, Xenopus laevis . PubMed: 17435750

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