Anti-FOXG1 antibody - ChIP Grade (ab18259)

Rabbit polyclonal FOXG1 antibody. Validated in WB, IHC, ChIP, ICC/IF and tested in Mouse, Rat, Human, Xenopus laevis. Cited in 47 publication(s). Independently reviewed in 11 review(s).

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ab18259 has been referenced in 53 publications.

  • Schafer ST  et al. Pathological priming causes developmental gene network heterochronicity in autistic subject-derived neurons. Nat Neurosci N/A:N/A (2019). IF . PubMed: 30617258
  • Peng JJ  et al. Repetitive transcranial magnetic stimulation promotes functional recovery and differentiation of human neural stem cells in rats after ischemic stroke. Exp Neurol 313:1-9 (2019). PubMed: 30529277
  • Goto-Silva L  et al. Computational fluid dynamic analysis of physical forces playing a role in brain organoid cultures in two different multiplex platforms. BMC Dev Biol 19:3 (2019). PubMed: 30841924
  • Boisvert EM  et al. Minocycline mitigates the effect of neonatal hypoxic insult on human brain organoids. Cell Death Dis 10:325 (2019). PubMed: 30975982
  • Dali R  et al. Characterization of a FOXG1:TLE1 transcriptional network in glioblastoma-initiating cells. Mol Oncol 12:775-787 (2018). PubMed: 29316219
  • Liu B  et al. Forced Expression of Foxg1 in the Cortical Hem Leads to the Transformation of Cajal-Retzius Cells into Dentate Granule Neurons. J Dev Biol 6:N/A (2018). PubMed: 29949945
  • Mattei C  et al. Generation of Neural Organoids from Human Embryonic Stem Cells Using the Rotary Cell Culture System: Effects of Microgravity on Neural Progenitor Cell Fate. Stem Cells Dev 27:848-857 (2018). PubMed: 29649415
  • Han X  et al. FoxG1 Directly Represses Dentate Granule Cell Fate During Forebrain Development. Front Cell Neurosci 12:452 (2018). PubMed: 30532694
  • Weise SC  et al. FOXG1 Regulates PRKAR2B Transcriptionally and Posttranscriptionally via miR200 in the Adult Hippocampus. Mol Neurobiol N/A:N/A (2018). PubMed: 30539330
  • Liu B  et al. Foxg1 deletion impairs the development of the epithalamus. Mol Brain 11:5 (2018). PubMed: 29394901
  • Chen J  et al. FOXG1 Expression Is Elevated in Glioma and Inhibits Glioma Cell Apoptosis. J Cancer 9:778-783 (2018). PubMed: 29581755
  • Tu J  et al. MicroRNA profiling during directed differentiation of cortical interneurons from human-induced pluripotent stem cells. FEBS Open Bio 8:502-512 (2018). PubMed: 29632804
  • Zhang M  et al. Highly efficient methods to obtain homogeneous dorsal neural progenitor cells from human and mouse embryonic stem cells and induced pluripotent stem cells. Stem Cell Res Ther 9:67 (2018). PubMed: 29544541
  • Hoffmann N  et al. DGCR8 Promotes Neural Progenitor Expansion and Represses Neurogenesis in the Mouse Embryonic Neocortex. Front Neurosci 12:281 (2018). PubMed: 29760646
  • Playne R  et al. Generation of dopamine neuronal-like cells from induced neural precursors derived from adult human cells by non-viral expression of lineage factors. J Stem Cells Regen Med 14:34-44 (2018). PubMed: 30018471
  • Bulstrode H  et al. Elevated FOXG1 and SOX2 in glioblastoma enforces neural stem cell identity through transcriptional control of cell cycle and epigenetic regulators. Genes Dev 31:757-773 (2017). PubMed: 28465359
  • Chau M  et al. Transplantation of iPS cell-derived neural progenitors overexpressing SDF-1a increases regeneration and functional recovery after ischemic stroke. Oncotarget 8:97537-97553 (2017). ICC/IF ; Human . PubMed: 29228630
  • Kimira Y  et al. Collagen-derived dipeptide prolyl-hydroxyproline promotes osteogenic differentiation through Foxg1. Cell Mol Biol Lett 22:27 (2017). PubMed: 29213293
  • Wilde JJ  et al. Diencephalic Size Is Restricted by a Novel Interplay Between GCN5 Acetyltransferase Activity and Retinoic Acid Signaling. J Neurosci 37:2565-2579 (2017). PubMed: 28154153
  • Subramanian L  et al. Dynamic behaviour of human neuroepithelial cells in the developing forebrain. Nat Commun 8:14167 (2017). IF ; Human . PubMed: 28139695
  • Bagley JA  et al. Fused cerebral organoids model interactions between brain regions. Nat Methods 14:743-751 (2017). PubMed: 28504681
  • Lancaster MA  et al. Guided self-organization and cortical plate formation in human brain organoids. Nat Biotechnol 35:659-666 (2017). PubMed: 28562594
  • Espuny-Camacho I  et al. Hallmarks of Alzheimer's Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain. Neuron 93:1066-1081.e8 (2017). PubMed: 28238547
  • Close JL  et al. Single-Cell Profiling of an In Vitro Model of Human Interneuron Development Reveals Temporal Dynamics of Cell Type Production and Maturation. Neuron 93:1035-1048.e5 (2017). PubMed: 28279351
  • Quadrato G  et al. Cell diversity and network dynamics in photosensitive human brain organoids. Nature 545:48-53 (2017). PubMed: 28445462
  • Toda T  et al. Nup153 Interacts with Sox2 to Enable Bimodal Gene Regulation and Maintenance of Neural Progenitor Cells. Cell Stem Cell 21:618-634.e7 (2017). PubMed: 28919367
  • Xu CC  et al. Abnormal mitochondrial transport and morphology as early pathological changes in human models of spinal muscular atrophy. Dis Model Mech 9:39-49 (2016). Human . PubMed: 26586529
  • Frullanti E  et al. Altered expression of neuropeptides in FoxG1-null heterozygous mutant mice. Eur J Hum Genet 24:252-7 (2016). PubMed: 25966633
  • Xu JC  et al. Cultured networks of excitatory projection neurons and inhibitory interneurons for studying human cortical neurotoxicity. Sci Transl Med 8:333ra48 (2016). PubMed: 27053772
  • Chen L  et al. Growth and metastasis of lung adenocarcinoma is potentiated by BMP4-mediated immunosuppression. Oncoimmunology 5:e1234570 (2016). PubMed: 27999749
  • Guye P  et al. Genetically engineering self-organization of human pluripotent stem cells into a liver bud-like tissue using Gata6. Nat Commun 7:10243 (2016). IF ; Human . PubMed: 26732624
  • Zemke M  et al. Loss of Ezh2 promotes a midbrain-to-forebrain identity switch by direct gene derepression and Wnt-dependent regulation. BMC Biol 13:103 (2015). PubMed: 26621269
  • Pancrazi L  et al. Foxg1 localizes to mitochondria and coordinates cell differentiation and bioenergetics. Proc Natl Acad Sci U S A 112:13910-5 (2015). PubMed: 26508630
  • Werner A  et al. Cell-fate determination by ubiquitin-dependent regulation of translation. Nature 525:523-7 (2015). PubMed: 26399832
  • Baek ST  et al. An AKT3-FOXG1-reelin network underlies defective migration in human focal malformations of cortical development. Nat Med 21:1445-54 (2015). IHC, ChIP . PubMed: 26523971
  • Reeh KA  et al. Ectopic TBX1 suppresses thymic epithelial cell differentiation and proliferation during thymus organogenesis. Development 141:2950-8 (2014). IHC-P ; Mouse . PubMed: 25053428
  • Kindberg AA  et al. An in vitro model of human neocortical development using pluripotent stem cells: cocaine-induced cytoarchitectural alterations. Dis Model Mech 7:1397-405 (2014). ICC/IF ; Human . PubMed: 25288682
  • Goubau C  et al. Platelet defects in congenital variant of Rett syndrome patients with FOXG1 mutations or reduced expression due to a position effect at 14q12. Eur J Hum Genet N/A:N/A (2013). Human . PubMed: 23632790
  • Weick JP  et al. Deficits in human trisomy 21 iPSCs and neurons. Proc Natl Acad Sci U S A 110:9962-7 (2013). PubMed: 23716668
  • Li JV  et al. Transcriptional repression of AIB1 by FoxG1 leads to apoptosis in breast cancer cells. Mol Endocrinol 27:1113-27 (2013). PubMed: 23660594
  • Lancaster MA  et al. Cerebral organoids model human brain development and microcephaly. Nature 501:373-9 (2013). PubMed: 23995685
  • Verginelli F  et al. Transcription factors FOXG1 and Groucho/TLE promote glioblastoma growth. Nat Commun 4:2956 (2013). PubMed: 24356439
  • Liu Y  et al. Directed differentiation of forebrain GABA interneurons from human pluripotent stem cells. Nat Protoc 8:1670-9 (2013). ICC . PubMed: 23928500
  • Sturm D  et al. Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma. Cancer Cell 22:425-37 (2012). PubMed: 23079654
  • Tian C  et al. Foxg1 has an essential role in postnatal development of the dentate gyrus. J Neurosci 32:2931-49 (2012). IHC-FoFr, WB ; Mouse . PubMed: 22378868
  • Fotaki V  et al. Wnt/ß-catenin signaling is disrupted in the extra-toes (Gli3(Xt/Xt) ) mutant from early stages of forebrain development, concomitant with anterior neural plate patterning defects. J Comp Neurol 519:1640-57 (2011). PubMed: 21452227
  • Wei Q & Condie BG A focused in situ hybridization screen identifies candidate transcriptional regulators of thymic epithelial cell development and function. PLoS One 6:e26795 (2011). PubMed: 22087235
  • Fasano CA  et al. Bmi-1 cooperates with Foxg1 to maintain neural stem cell self-renewal in the forebrain. Genes Dev 23:561-74 (2009). WB . PubMed: 19270157
  • Danesin C  et al. Integration of telencephalic Wnt and hedgehog signaling center activities by Foxg1. Dev Cell 16:576-87 (2009). ChIP ; Zebrafish . PubMed: 19386266
  • Chan DW  et al. Overexpression of FOXG1 contributes to TGF-beta resistance through inhibition of p21WAF1/CIP1 expression in ovarian cancer. Br J Cancer 101:1433-43 (2009). WB, IHC ; Human . PubMed: 19755996
  • Friedrichs M  et al. Lamination of the cerebral cortex is disturbed in Gli3 mutant mice. Dev Biol 318:203-14 (2008). PubMed: 18448089
  • Wu H  et al. Integrative genomic and functional analyses reveal neuronal subtype differentiation bias in human embryonic stem cell lines. Proc Natl Acad Sci U S A 104:13821-6 (2007). PubMed: 17693548
  • Regad T  et al. The neural progenitor-specifying activity of FoxG1 is antagonistically regulated by CKI and FGF. Nat Cell Biol 9:531-40 (2007). IHC-P, IHC-Fr ; Mouse, Xenopus laevis . PubMed: 17435750

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