Product nameAnti-FOXM1 antibody
See all FOXM1 primary antibodies
DescriptionRabbit polyclonal to FOXM1
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Mouse, Rat, Human
Recombinant fragment corresponding to Human FOXM1 aa 1-350 (N terminal).
Database link: Q08050
- WB: SW620, SKOV3, A-549, A-431 and HeLa cell lysates; Mouse heart, spleen and thymus tissue lysates; Rat thymus tissue lysate.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol, 49% PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab180710 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/2000. Predicted molecular weight: 84 kDa.|
FunctionTranscriptional activatory factor. May play a role in the control of cell proliferation.
Tissue specificityExpressed in thymus, testis, small intestine, colon followed by ovary. Appears to be expressed only in adult organs containing proliferating/cycling cells or in response to growth factors. Also expressed in epithelial cell lines derived from tumors. Not expressed in resting cells. Isoform 2 is highly expressed in testis.
Sequence similaritiesContains 1 fork-head DNA-binding domain.
Developmental stageEmbryonic expression pattern: liver, lung, intestine, kidney, urinary tract; adult expression pattern: intestine, colon, testis and thymus.
DomainWithin the protein there is a domain which acts as a transcriptional activator. Insertion of a splicing sequence within it inactivates this transcriptional activity, as it is the case for isoform 4.
modificationsPhosphorylated in M (mitotic) phase.
- Information by UniProt
- FKHL16 antibody
- Forkhead box M1 antibody
- Forkhead box protein M1 antibody
All lanes : Anti-FOXM1 antibody (ab180710) at 1/1000 dilution
Lane 1 : SW620 cell lysate
Lane 2 : SKOV3 cell lysate
Lane 3 : A-549 cell lysate
Lane 4 : A-431 cell lysate
Lane 5 : HeLa cell lysate
Lane 6 : Mouse heart tissue lysate
Lane 7 : Mouse spleen tissue lysate
Lane 8 : Mouse thymus tissue lysate
Lane 9 : Rat thymus tissue lysate
Lysates/proteins at 25 µg per lane.
All lanes : HRP Goat Anti-Rabbit IgG (H+L)
Developed using the ECL technique.
Predicted band size: 84 kDa
Exposure time: 90 seconds
This product has been referenced in:
- Blanchard TG et al. Identification of Cross Talk between FoxM1 and RASSF1A as a Therapeutic Target of Colon Cancer. Cancers (Basel) 11:N/A (2019). Read more (PubMed: 30744076) »
- Rui QH et al. Effect of lncRNA HULC knockdown on rat secreting pituitary adenoma GH3 cells. Braz J Med Biol Res 52:e7728 (2019). Read more (PubMed: 30994730) »