Overview

  • Product name

  • Description

    Rabbit polyclonal to FOXRED1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment within Human FOXRED1 (internal sequence). The exact sequence is proprietary.
    Database link: Q96CU9

  • Positive control

    • WB: A431 and Raji whole cell lysates. IHC-P: Human lung cancer tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab228628 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/1000.
WB 1/500 - 1/3000. Predicted molecular weight: 53 kDa.

Target

  • Function

    Required for the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) (PubMed:20858599, PubMed:25678554). Involved in mid-late stages of complex I assembly (PubMed:25678554).
  • Involvement in disease

    Mitochondrial complex I deficiency
  • Cellular localization

    Mitochondrion inner membrane. According to a report, it is associated with the matrix face of the mitochondrial inner membrane and does not contain any transmembrane region. However, one transmembrane domain is clearly predicted by different methods (Probable).
  • Information by UniProt
  • Database links

  • Alternative names

    • FAD dependent oxidoreductase domain containing 1 antibody
    • FAD dependent oxidoreductase domain containing protein 1 antibody
    • FAD-dependent oxidoreductase domain-containing protein 1 antibody
    • FOXRED 1 antibody
    • FOXRED1 antibody
    • FP634 antibody
    • FXRD1_HUMAN antibody
    • H17 antibody
    see all

Images

  • All lanes : Anti-FOXRED1 antibody (ab228628) at 1/1000 dilution

    Lane 1 : A431 (human epidermoid carcinoma cell line) whole cell lysate
    Lane 2 : Raji (human Burkitt's lymphoma cell line) whole cell lysate

    Lysates/proteins at 30 µg per lane.

    Developed using the ECL technique.

    Predicted band size: 53 kDa



    7.5% SDS-PAGE

  • Paraffin-embedded human lung cancer tissue stained for FOXRED1 with ab228628 at 1/300 dilution in immunohistochemical analysis.

References

ab228628 has not yet been referenced specifically in any publications.

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