Overview

  • Product name

  • Description

    Rabbit polyclonal to FPGS
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human FPGS aa 100-200 (internal sequence). The exact sequence is proprietary.
    Database link: Q05932

  • Positive control

    • Human liver carcinoma
  • General notes

    Previously labelled as Folylpolyglutamate synthase. 

Properties

Applications

Our Abpromise guarantee covers the use of ab82055 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Boil tissue section in 10mM Citrate buffer, pH 6.0 for 10-20 min followed by cooling at RT for 20 min.

Target

  • Function

    Conversion of folates to polyglutamate derivatives. This allows tissues to concentrate folate at higher levels than in plasma.
  • Pathway

    Cofactor biosynthesis; tetrahydrofolylpolyglutamate biosynthesis.
  • Sequence similarities

    Belongs to the folylpolyglutamate synthase family.
  • Cellular localization

    Mitochondrion. Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • EC 6.3.2.17 antibody
    • FOLC antibody
    • FOLC_HUMAN antibody
    • Folylpoly gamma glutamate synthetase antibody
    • Folylpoly-gamma-glutamate synthetase antibody
    • Folylpolyglutamate synthase antibody
    • Folylpolyglutamate synthase mitochondrial antibody
    • FPGS antibody
    • mitochondrial antibody
    • OTTHUMP00000022201 antibody
    • OTTHUMP00000022202 antibody
    • Tetrahydrofolate synthase antibody
    • Tetrahydrofolylpolyglutamate synthase antibody
    see all

Images

  • ab82055, at 1/100 diultion, staining of Formalin-fixed, paraffin-embedded, human liver carcinoma using Immunohistochemistry

References

ab82055 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab82055.
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