Recombinant Anti-FPR3 antibody [EPR11865] (ab172908)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR11865] to FPR3
- Suitable for: WB, Flow Cyt
- Reacts with: Human
Related conjugates and formulations
Overview
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Product name
Anti-FPR3 antibody [EPR11865]
See all FPR3 primary antibodies -
Description
Rabbit monoclonal [EPR11865] to FPR3 -
Host species
Rabbit -
Tested applications
Suitable for: WB, Flow Cytmore details
Unsuitable for: ICC/IF,IHC-P or IP -
Species reactivity
Reacts with: Human
Does not react with: Mouse, Rat -
Immunogen
Synthetic peptide within Human FPR3 aa 1-100 (Cysteine residue). The exact sequence is proprietary.
Database link: P25089 -
Positive control
- Human thymus, Jurkat, NCI-H460 cell lysates, NCI-H460 cells
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General notes
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading...
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Purity
Tissue culture supernatant -
Clonality
Monoclonal -
Clone number
EPR11865 -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Related Products
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab172908 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
1/1000 - 1/5000. Predicted molecular weight: 40 kDa.
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Flow Cyt |
1/10 - 1/100.
ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody. |
Notes |
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WB
1/1000 - 1/5000. Predicted molecular weight: 40 kDa. |
Flow Cyt
1/10 - 1/100. ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody. |
Target
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Function
Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 2359 Human
- Omim: 136539 Human
- SwissProt: P25089 Human
- Unigene: 445466 Human
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Alternative names
- FML2_HUMAN antibody
- FMLP related receptor II antibody
- FMLP-R-II antibody
see all
Images
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Flow cytometric analysis of NCI-H460 cells labeling FPR3 with ab172908 (red) or a rabbit IgG (negative) (green).
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All lanes : Anti-FPR3 antibody [EPR11865] (ab172908) at 1/1000 dilution
Lane 1 : Human thymus
Lane 2 : Jurkat cell lysate
Lane 3 : NCI-H460 cell lysate
Lysates/proteins at 10 µg per lane.
Predicted band size: 40 kDa
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab172908 has not yet been referenced specifically in any publications.