Anti-FPRL1/RFP antibody (ab203129)
Key features and details
- Rabbit polyclonal to FPRL1/RFP
- Suitable for: IHC-P, Flow Cyt
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Overview
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Product name
Anti-FPRL1/RFP antibody
See all FPRL1/RFP primary antibodies -
Description
Rabbit polyclonal to FPRL1/RFP -
Host species
Rabbit -
Tested applications
Suitable for: IHC-P, Flow Cytmore details -
Species reactivity
Reacts with: Mouse, Rat, Human -
Immunogen
Synthetic peptide within Human FPRL1/RFP aa 84-100 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
Sequence:SMAMGEKWPFGWFLCKL
Database link: P25090 -
General notes
This product was previously labelled as FPRL1
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.09% Sodium azide
Constituents: 0.01% BSA, 50% Glycerol
Aqueous buffered solution. -
Concentration information loading... -
Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Conjugation kits
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Isotype control
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Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab203129 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P | 1/100 - 1/500. (or 1/50 - 1/200 using a fluorescent secondary antibody). |
|
| Flow Cyt | 1/20 - 1/100. |
Target
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Function
Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4). -
Tissue specificity
Expressed abundantly in the lung and neutrophils. Also found in the spleen and testis. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 2358 Human
- Entrez Gene: 14294 Mouse
- Entrez Gene: 681706 Rat
- Omim: 136538 Human
- SwissProt: P25090 Human
- SwissProt: O08790 Mouse
- Unigene: 99855 Human
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Alternative names
- ALXR antibody
- FMLP-R-I antibody
- FMLP-R-II antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FPRL1/RFP antibody (ab203129)
Immunohistochemical analysis of formalin-fixed, paraffin-embedded injured rat spinal cord tissue labeling FPRL1/RFP with ab203129 at 1/200 dilution overnight at 4°C, followed by Goat Anti-Rabbit IgG, Alexa Fluor 647 conjugated secondary antibody at 1/200 dilution for 40 minutes at 37°C.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FPRL1/RFP antibody (ab203129)Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human pneumonitis tissue labeling FPRL1/RFP with ab203129 at 1/200 dilution, followed by conjugation to the secondary antibody and DAB staining.
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Flow Cytometry - Anti-FPRL1/RFP antibody (ab203129)Flow cytometric analysis of Mouse splenocytes labeling FPRL1/RFP with ab203129 at 1/50 dilution, followed by incubation with Goat Anti-Rabbit IgG FITC conjugated secondary at 1/100 dilution (green) compared to control cells (blue).
Protocols
Datasheets and documents
References (0)
ab203129 has not yet been referenced specifically in any publications.
