Key features and details
- Rabbit polyclonal to FPRL1/RFP
- Suitable for: WB, ICC/IF
- Reacts with: Human
- Isotype: IgG
Product nameAnti-FPRL1/RFP antibody
See all FPRL1/RFP primary antibodies
DescriptionRabbit polyclonal to FPRL1/RFP
Tested applicationsSuitable for: WB, ICC/IFmore details
Species reactivityReacts with: Human
Synthetic peptide corresponding to Human FPRL1/RFP (C terminal) conjugated to keyhole limpet haemocyanin.
- HL60 cells and HL60 cell extract.
This product was previously labelled as FPRL1
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Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferpH: 7.20
Preservative: 0.05% Sodium azide
Constituents: 0.0268% PBS, 50% Glycerol, 0.01% BSA
Concentration information loading...
PurityProtein G purified
Our Abpromise guarantee covers the use of ab63023 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/6000. Detects a band of approximately 38 kDa (predicted molecular weight: 39 kDa).|
FunctionLow affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4).
Tissue specificityExpressed abundantly in the lung and neutrophils. Also found in the spleen and testis.
Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
Cellular localizationCell membrane.
- Information by UniProt
- ALXR antibody
- FMLP-R-I antibody
- FMLP-R-II antibody
Anti-FPRL1/RFP antibody (ab63023) at 1/6000 dilution + Extracts of HL60 cells
Predicted band size: 39 kDa
Observed band size: 38 kDa why is the actual band size different from the predicted?
Immunofluorescent analysis of HL60 cells using ab63023 (green) at 1:600. Nucleus have been labeled with PI (red).
ab63023 has been referenced in 1 publication.
- Xu C et al. CSA13 inhibits colitis-associated intestinal fibrosis via a formyl peptide receptor like-1 mediated HMG-CoA reductase pathway. Sci Rep 7:16351 (2017). PubMed: 29180648