Overview

  • Product name

  • Description

    Rabbit polyclonal to FRK
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 276-473 of Human FRK (UniProt ID: P42685).

  • Positive control

    • 293T, A431, H1299, HeLaS3, HepG2, Raji cells; Molt4 whole cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab154032 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 58 kDa.

Target

  • Function

    Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation possibly by reducing its binding to NEDD4. May function as a tumor suppressor.
  • Tissue specificity

    Restricted to cells lines derived from tissues of lymphoid, brain, breast, colon and bladder origin.
  • Sequence similarities

    Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
    Contains 1 protein kinase domain.
    Contains 1 SH2 domain.
    Contains 1 SH3 domain.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • Beta cell Src homology tyrosine kinase antibody
    • BSK antibody
    • BSK/IYK antibody
    • C85044 antibody
    • Frk antibody
    • Frk fyn related kinase antibody
    • FRK_HUMAN antibody
    • FYN related kinase antibody
    • FYN-related kinase antibody
    • GASK antibody
    • Gastrointestinal associated kinase antibody
    • Gastrointestinal associated tyrosine kinase antibody
    • GTK antibody
    • GTK, mouse, homolog of antibody
    • Intestine tyrosine kinase antibody
    • Nuclear tyrosine protein kinase RAK antibody
    • Protein-tyrosine kinase 5 antibody
    • PTK5 antibody
    • PTK5 protein tyrosine kinase 5 antibody
    • RAK antibody
    • Tyrosine protein kinase FRK antibody
    • Tyrosine-protein kinase FRK antibody
    see all

Images

  • Anti-FRK antibody (ab154032) at 1/500 dilution + Molt4 whole cell lysate at 30 µg

    Predicted band size: 58 kDa



    7.5% SDS PAGE

References

ab154032 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab154032.
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