Overview

  • Product name

    FSL-1, TLR2/6 agonist
  • Description

    TLR2/6 agonist
  • Biological description

    Toll-like receptor 2/6 (TLR2/6) agonist. Anti-herpetic activity. Exhibits clathrin-dependent internalization. Induces TNF-α in macrophages. NF-κB activator. Active in vivo.
  • CAS Number

    322455-70-9
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Shamsul HM  et al. The Toll-like receptor 2 (TLR2) ligand FSL-1 is internalized via the clathrin-dependent endocytic pathway triggered by CD14 and CD36 but not by TLR2. Immunology 130:262-72 (2010). Read more (PubMed: 20113368) »
  • Rose WA  et al. FSL-1, a bacterial-derived toll-like receptor 2/6 agonist, enhances resistance to experimental HSV-2 infection. Virol J 6:195 (2009). Read more (PubMed: 19903337) »
  • Kiura K  et al. The diacylated lipopeptide FSL-1 induces TLR2-mediated Th2 responses. FEMS Immunol Med Microbiol 48:44-55 (2006). Read more (PubMed: 16965351) »

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