Anti-FSTL1/FRP antibody (ab71548)
Key features and details
- Rabbit polyclonal to FSTL1/FRP
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
Get better batch-to-batch reproducibility with a recombinant antibody
- Research with confidence – consistent and reproducible results with every batch
- Long-term and scalable supply – powered by recombinant technology for fast production
- Success from the first experiment – confirmed specificity through extensive validation
- Ethical standards compliant – production is animal-free
Overview
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Product name
Anti-FSTL1/FRP antibody
See all FSTL1/FRP primary antibodies -
Description
Rabbit polyclonal to FSTL1/FRP -
Host species
Rabbit -
Tested applications
Suitable for: IHC-P, WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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General notes
We are constantly working hard to ensure we provide our customers with best in class antibodies. As a result, we are pleased to offer this antibody in a purified format as of 19th February 2018. The following lots is/are still unpurified and still in stock as of 19th February 2018 - GR200980-7, GR200980-9, GR200980-10. Lot numbers other than GR200980-7, GR200980-9, GR200980-10 will be purified. Please note that the dilutions may need to be adjusted accordingly. Purified antibodies have the advantage of being enriched for the fraction of immunoglobulin that specifically reacts with the target antigen and for having a reduction of serum proteins.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle. -
Storage buffer
Constituents: 0.92% Glycerol, 1.21% Tris, 2% Sucrose -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab71548 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
Use at an assay dependent concentration.
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WB | (1) |
Use at an assay dependent concentration.
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Notes |
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IHC-P
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. |
Target
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Function
May modulate the action of some growth factors on cell proliferation and differentiation. Binds heparin. -
Tissue specificity
Overexpressed in synovial tissues from rheumatoid arthritis. -
Sequence similarities
Contains 2 EF-hand domains.
Contains 1 follistatin-like domain.
Contains 1 Kazal-like domain.
Contains 1 VWFC domain. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 11167 Human
- Entrez Gene: 14314 Mouse
- Entrez Gene: 79210 Rat
- Omim: 605547 Human
- SwissProt: Q12841 Human
- SwissProt: Q62356 Mouse
- SwissProt: Q62632 Rat
- Unigene: 269512 Human
see all -
Alternative names
- Anti FSTL1 antibody
- FLJ50214 antibody
- FLJ52277 antibody
see all
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (7)
ab71548 has been referenced in 7 publications.
- Liu Y et al. FSTL1 aggravates cigarette smoke-induced airway inflammation and airway remodeling by regulating autophagy. BMC Pulm Med 21:45 (2021). PubMed: 33509151
- Chen L & Liu Z Downregulation of FSTL-1 attenuates the inflammation injury during Streptococcus pneumoniae infection by inhibiting the NLRP3 and TLR4/NF-?B signaling pathway. Mol Med Rep 20:5345-5352 (2019). PubMed: 31638229
- Peng X et al. Follistatin-like protein 1 knockdown elicits human gastric cancer cell apoptosis via a STAT6-dependent pathway. Oncol Rep 42:2806-2813 (2019). PubMed: 31578589
- Zhang M et al. BMP-2 overexpression augments vascular smooth muscle cell motility by upregulating myosin Va via Erk signaling. Oxid Med Cell Longev 2014:294150 (2014). PubMed: 24790701
- Yucel G et al. State-dependent signaling by Cav1.2 regulates hair follicle stem cell function. Genes Dev 27:1217-22 (2013). PubMed: 23752588
- Gao MH et al. beta(1)-Adrenergic receptor vs adenylyl cyclase 6 expression in cardiac myocytes: differences in transgene localization and intracellular signaling. Cell Signal 22:584-9 (2010). PubMed: 19932173
- Liu S et al. FRP inhibits ox-LDL-induced endothelial cell apoptosis through an Akt-NF-{kappa}B-Bcl-2 pathway and inhibits endothelial cell apoptosis in an apoE-knockout mouse model. Am J Physiol Endocrinol Metab 299:E351-63 (2010). WB, IHC-P ; Mouse . PubMed: 20530739