Overview

  • Product name

    Anti-FTSJ2 antibody [2372C6a]
  • Description

    Mouse monoclonal [2372C6a] to FTSJ2
  • Host species

    Mouse
  • Tested applications

    Suitable for: WB, Dot blotmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment (Human)

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer

    pH: 7.40
    Preservative: 0.05% Sodium azide
    Constituents: PBS, 0.0225% Potassium chloride, 0.03% Potassium phosphate, 0.1312% Sodium phosphate, 0.812% Sodium chloride, 1% BSA
  • Concentration information loading...
  • Purity

    Protein G purified
  • Purification notes

    Purified using protein G column chromatography, from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
  • Clonality

    Monoclonal
  • Clone number

    2372C6a
  • Isotype

    IgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab60068 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Detects a band of approximately 34 kDa (predicted molecular weight: 27 kDa).
Dot blot Use at an assay dependent dilution.

Target

  • Function

    Probable methyltransferase.
  • Tissue specificity

    Widely expressed, with highest expression in muscle, placenta, and heart.
  • Sequence similarities

    Belongs to the methyltransferase superfamily. RlmE family.
  • Cellular localization

    Nucleus > nucleolus.
  • Information by UniProt
  • Database links

  • Alternative names

    • FJH1 antibody
    • FTSJ2 antibody
    • MRM2 antibody
    • Protein ftsJ homolog 2 antibody
    • Putative ribosomal RNA methyltransferase 2 antibody
    • Ribosomal RNA methyltransferase 2 antibody
    • RRMJ2_HUMAN antibody
    • rRNA (uridine-2''-O-)-methyltransferase antibody
    see all

Images

  • Western blot analysis of immunized recombinant protein, using ab60068.

References

This product has been referenced in:

  • Garone C  et al. Defective mitochondrial rRNA methyltransferase MRM2 causes MELAS-like clinical syndrome. Hum Mol Genet 26:4257-4266 (2017). Read more (PubMed: 28973171) »
  • Lee KW & Bogenhagen DF Assignment of 2'-O-methyltransferases to modification sites on the mammalian mitochondrial large subunit 16 S ribosomal RNA (rRNA). J Biol Chem 289:24936-42 (2014). Human . Read more (PubMed: 25074936) »
See all 3 Publications for this product

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