Overview

  • Product name

    Fumonisin B2, cell proliferation inhibitor
  • Description

    Cell proliferation inhibitor and apoptosis inducer.
  • Biological description

    Cell proliferation inhibitor and apoptosis inducer. Mycotoxin, inhibits sphingolipid biosynthesis. Toxicological effects in vivo. Carcinogenic. Structural analog of Fumonisin B1 (ab142433). Active in vivo and in vitro.
  • Purity

    > 97%
  • CAS Number

    116355-84-1
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    2-[2-[19-Amino-6-(3,4-dicarboxybutanoyloxy)-16,18-dihydroxy-5,9-dimethylicosan-7-yl]oxy-2-oxoethyl]butanedioic acid
  • Molecular weight

    705.80
  • Molecular formula

    C34H59NO14
  • PubChem identifier

    3432
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 25 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCCCC(C)C(C(CC(C)CCCCCCC(CC(C(C)N)O)O)OC(=O)CC(CC(=O)O)C(=O)O)OC(=O)CC(CC(=O)O)C(=O)O
  • Source

    Fusarium moniliforme

  • Research areas

References

This product has been referenced in:

  • Abbas HK  et al. Biological activities of fumonisins, mycotoxins from Fusarium moniliforme, in jimsonweed (Datura stramonium L.) and mammalian cell cultures. Toxicon 31:345-53 (1993). Read more (PubMed: 8470138) »
  • Gelderblom WC  et al. Fumonisins: isolation, chemical characterization and biological effects. Mycopathologia 117:11-6 (1992). Read more (PubMed: 1513367) »
  • Wang E  et al. Inhibition of sphingolipid biosynthesis by fumonisins. Implications for diseases associated with Fusarium moniliforme. J Biol Chem 266:14486-90 (1991). Read more (PubMed: 1860857) »

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab142434.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
For licensing inquiries, please contact partnerships@abcam.com

Sign up