Key features and details
- PDE inhibitor. Selective cytochrome P450IA2 inhibitor. Methyl xanthine derivative.
- CAS Number: 80288-49-9
- Purity: > 98%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Product nameFurafylline, PDE inhibitor
DescriptionPDE inhibitor. Selective cytochrome P450IA2 inhibitor. Methyl xanthine derivative.
PDE inhibitor. Selective cytochrome P450IA2 inhibitor (IC50 = 2.4 μM). Methyl xanthine derivative. Shows an expanded duration of action compared to theophylline (ab142599) in vivo. Orally active.
Storage instructionsStore at Room Temperature. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab146021 has not yet been referenced specifically in any publications.