Key features and details
- Inhibitor of the Na+/2Cl-/K+ cotransporter. Also GABAA antagonist.
- CAS Number: 54-31-9
- Purity: > 99%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Product nameFurosemide, Na+/2Cl-/K+ cotransporter inhibitor
DescriptionInhibitor of the Na+/2Cl-/K+ cotransporter. Also GABAA antagonist.
Inhibitor of the Na+/2Cl-/K+ cotransporter. Loop diuretic. Also acts as a non-competitive antagonist at GABAA receptors displaying approx. 100-fold greater selectivity for α6-containing receptors over α1-containing receptors.
Chemical name5-(Aminosulfonyl)-4-chloro-2-[(2-furanylmethyl)amino]benzoic acid
Storage instructionsStore at Room Temperature. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Receptors & Transporters
- Ion pumps / transporter
- Na+/2Cl-/K+ cotransporter
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab120314 has not yet been referenced specifically in any publications.