Overview

  • Product name

    Furosemide, Na+/2Cl-/K+ cotransporter inhibitor
  • Description

    Inhibitor of the Na+/2Cl-/K+ cotransporter. Also GABAA antagonist.
  • Biological description

    Inhibitor of the Na+/2Cl-/K+ cotransporter. Loop diuretic. Also acts as a non-competitive antagonist at GABAA receptors displaying approx. 100-fold greater selectivity for α6-containing receptors over α1-containing receptors.
  • Purity

    > 99%
  • CAS Number

    54-31-9
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Guyon A  et al. Furosemide modulation of GABA(A) receptors in dopaminergic neurones of the rat substantia nigra. Neuropharmacology 43:750-63 (2002). Read more (PubMed: 12367620) »
  • Thompson SA  et al. Residues in transmembrane domains I and II determine gamma-aminobutyric acid type AA receptor subtype-selective antagonism by furosemide. Mol Pharmacol 55:993-9 (1999). Read more (PubMed: 10347239) »
  • Romano G  et al. The site of action of furosemide. Pharmacol Res 37:409-19 (1998). Read more (PubMed: 9642037) »

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab120314.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
For licensing inquiries, please contact partnerships@abcam.com

Sign up