Key features and details
- Rabbit polyclonal to FUZ
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-FUZ antibody
See all FUZ primary antibodies
DescriptionRabbit polyclonal to FUZ
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat, Cow
Recombinant fragment, corresponding to a region within amino acids 76-348 of Human FUZ (AAH04445).
- HCT116 whole cell lysate; Human Gastric carcinoma and RT2 xenograft tissues.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 78.99% PBS, 1% BSA, 20% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
Purification notesab111842 is purified by antigen-affinity chromatography.
Our Abpromise guarantee covers the use of ab111842 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 46 kDa.|
|IHC-P||1/100 - 1/500. Suggested antigen retrieval using heat mediated 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0)|
FunctionProbable planar cell polarity effector involved in cilium biogenesis. May regulate protein and membrane transport to the cilium. May regulate the morphogenesis of hair follicles which depends on functional primary cilia.
Sequence similaritiesBelongs to the fuzzy family.
Cellular localizationCytoplasm. Cytoplasm > cytoskeleton.
- Information by UniProt
- FLJ22688 antibody
- fuz antibody
- FUZZY_HUMAN antibody
Anti-FUZ antibody (ab111842) at 1/1000 dilution + HCT116 cell line lysate at 30 µg
Predicted band size: 46 kDa
10% SDS PAGE
ab111842, at 1/500 dilution, staining FUZ in Formalin-fixed, Paraffin-embedded Human Gastric carcinoma tissue by Immunohistochemistry.
ab111842, at 1/500 dilution, staining FUZ in Formalin-fixed, Paraffin-embedded RT2 xenograft tissue by Immunohistochemistry.
ab111842 has been referenced in 1 publication.
- Chen ZS et al. Planar cell polarity gene Fuz triggers apoptosis in neurodegenerative disease models. EMBO Rep 19:N/A (2018). PubMed: 30026307