Anti-FVT1 antibody (ab153960)
- Datasheet
- References
- Protocols
Overview
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Product name
Anti-FVT1 antibody
See all FVT1 primary antibodies -
Description
Rabbit polyclonal to FVT1 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Cow
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Immunogen
Recombinant fragment, corresponding to a region within amino acids 65-296 of Human FVT1 (Uniprot ID Q06136)
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Positive control
- 293T | A431 | Jurkat | Raji whole cell lysates.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab153960 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/500 - 1/3000. Predicted molecular weight: 36 kDa. |
Target
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Function
Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS). -
Tissue specificity
Expressed in all tissues examined. Highest expression in placenta. High expression in lung, kidney, stomach and small intestine, low expression in heart, spleen and skeletal muscle. Weakly expressed in normal hematopoietic tissues. Higher expression in some T-cell malignancies and PHA-stimulated lymphocytes. -
Pathway
Lipid metabolism; sphingolipid metabolism. -
Involvement in disease
A chromosomal aberration involving KDSR is a cause of follicular lymphoma; also known as type II chronic lymphatic leukemia. Translocation t(2;18)(p11;q21) with a Ig J kappa chain region (PubMed:8417785). -
Sequence similarities
Belongs to the short-chain dehydrogenases/reductases (SDR) family. -
Cellular localization
Endoplasmic reticulum membrane. - Information by UniProt
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Database links
- Entrez Gene: 505558 Cow
- Entrez Gene: 2531 Human
- Entrez Gene: 70750 Mouse
- Entrez Gene: 360833 Rat
- Omim: 136440 Human
- SwissProt: Q2KIJ5 Cow
- SwissProt: Q06136 Human
- SwissProt: Q6GV12 Mouse
see all -
Alternative names
- 3 dehydrosphinganine reductase antibody
- 3 ketodihydrosphingosine reductase antibody
- 3-dehydrosphinganine reductase antibody
see all
Images
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Western blot - Anti-FVT1 antibody (ab153960)Anti-FVT1 antibody (ab153960) at 1/1000 dilution + 293T whole cell lysate at 30 µg
Predicted band size: 36 kDa
10% SDS PAGE
Protocols
References
ab153960 has not yet been referenced specifically in any publications.
