Recombinant Anti-FBXL19 antibody [EPR11957] (ab172961)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR11957] to FBXL19
- Suitable for: WB, ICC/IF
- Reacts with: Mouse, Human
Related conjugates and formulations
Overview
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Product name
Anti-FBXL19 antibody [EPR11957]
See all FBXL19 primary antibodies -
Description
Rabbit monoclonal [EPR11957] to FBXL19 -
Host species
Rabbit -
Tested applications
Suitable for: WB, ICC/IFmore details
Unsuitable for: Flow Cyt,IHC-P or IP -
Species reactivity
Reacts with: Mouse, Human
Predicted to work with: Rat -
Immunogen
Synthetic peptide within Human FBXL19 aa 500-600 (Cysteine residue). The exact sequence is proprietary.
Database link: Q6PCT2 -
Positive control
- HT1080, A549 and mouse testis lysates; A549 cells.
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General notes
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading...
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Purity
Tissue culture supernatant -
Clonality
Monoclonal -
Clone number
EPR11957 -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab172961 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB | (1) |
1/1000 - 1/5000. Predicted molecular weight: 76 kDa.
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ICC/IF |
1/50 - 1/100.
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Notes |
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WB
1/1000 - 1/5000. Predicted molecular weight: 76 kDa. |
ICC/IF
1/50 - 1/100. |
Target
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Function
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. -
Sequence similarities
Contains 1 CXXC-type zinc finger.
Contains 1 F-box domain.
Contains 6 LRR (leucine-rich) repeats.
Contains 1 PHD-type zinc finger. - Information by UniProt
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Database links
- Entrez Gene: 54620 Human
- Entrez Gene: 233902 Mouse
- Entrez Gene: 308999 Rat
- GenBank: BC059173 Human
- Omim: 609085 Human
- SwissProt: Q6PCT2 Human
- SwissProt: Q6PB97 Mouse
- Unigene: 152149 Human
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Alternative names
- CXXC11 antibody
- F-box and leucine-rich repeat protein 19 antibody
- F-box/LRR-repeat protein 19 antibody
see all
Images
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab172961 has been referenced in 2 publications.
- Jin L et al. ETS1-activated SNHG10 exerts oncogenic functions in glioma via targeting miR-532-3p/FBXL19 axis. Cancer Cell Int 20:589 (2020). PubMed: 33298070
- Acharya A et al. miR-26 suppresses adipocyte progenitor differentiation and fat production by targeting Fbxl19. Genes Dev 33:1367-1380 (2019). PubMed: 31488578