Product nameG 418 sulfate (aqueous), aminoglycoside antibiotic agent
DescriptionAminoglycoside antibiotic agent.
- Antibiotic G418
- G418 Sulfate
- Geneticin (G418) Sulfate
- Geneticin Sulfate
Aminoglycoside antibiotic. Has a broad range of antibacterial activity both in vivo and in vitro. Also active against protozoa and helminths. Inhibits protein synthesis by blocking the elongation step. Routinely used as a selective agent in cell culture gene selection applications.
Storage instructionsStore at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSupplied in water (40 mg/ml)
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
This product has been referenced in:
- Bar-Nun S et al. G-418, an elongation inhibitor of 80 S ribosomes. Biochim Biophys Acta 741:123-7 (1983). Read more (PubMed: 6193810) »
- Waitz JA et al. Biological activity of antibiotic G-418, a new micromonospora-produced aminoglycoside with activity against protozoa and helminths. Antimicrob Agents Chemother 6:579-81 (1974). Read more (PubMed: 15825308) »
- Wagman GH et al. Antibiotic G-418, a new Micromonospora-produced aminoglycoside with activity against protozoa and helminths: fermentation, isolation, and preliminary characterization. Antimicrob Agents Chemother 6:144-9 (1974). Read more (PubMed: 15828184) »