Key features and details
- Rabbit polyclonal to G-6-Pase
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-G-6-Pase antibody
See all G-6-Pase primary antibodies
DescriptionRabbit polyclonal to G-6-Pase
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Cat, Macaque monkey
Synthetic peptide corresponding to Human G-6-Pase aa 300 to the C-terminus (C terminal) conjugated to keyhole limpet haemocyanin.
(Peptide available as
- WB: HepG2 and Hek293 whole cell lysate
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help.
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab93857 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 µg/ml. Detects a band of approximately 37 kDa (predicted molecular weight: 40 kDa).|
FunctionHydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. Forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels.
PathwayCarbohydrate biosynthesis; gluconeogenesis.
Involvement in diseaseDefects in G6PC are the cause of glycogen storage disease type 1A (GSD1A) [MIM:232200]. A metabolic disorder characterized by impairment of terminal steps of glycogenolysis and gluconeogenesis. Patients manifest a wide range of clinical symptoms and biochemical abnormalities, including hypoglycemia, severe hepatomegaly due to excessive accumulation of glycogen, kidney enlargement, growth retardation, lactic acidemia, hyperlipidemia, and hyperuricemia.
Sequence similaritiesBelongs to the glucose-6-phosphatase family.
Cellular localizationEndoplasmic reticulum membrane.
- Information by UniProt
- AW107337 antibody
- G-6-Pase antibody
- G6Pase antibody
All lanes : Anti-G-6-Pase antibody (ab93857) at 1 µg/ml
All lanes :
All lanes : Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/50000 dilution
Predicted band size: 40 kDa
Observed band size: 37 kDa why is the actual band size different from the predicted?
Blocking buffer: 3% milk
Gel type: MOPS
Exposure Time: 12 minutes
ab93857 has been referenced in 1 publication.
- Karas K et al. The Dichotomous Nature of AZ5104 (an EGFR Inhibitor) Towards ROR? and ROR?T. Int J Mol Sci 20:N/A (2019). PubMed: 31744223