Overview

  • Product name

    Anti-G protein alpha S antibody
    See all GNAS primary antibodies
  • Description

    Rabbit polyclonal to G protein alpha S
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow, Pig
  • Immunogen

    Recombinant protein fragment corresponding to a region within amino acids 164 - 394 of Human G protein alpha S (AAH02722).

  • Positive control

    • 293T, A431, H1299, HeLa, HepG2, MOLT4 and Raji cell lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab97629 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 46 kDa.

Target

  • Relevance

    Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The Gs protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli. Alternative splicing of downstream exons of the GNAS gene is observed, which results in different forms of the stimulatory G protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses. Multiple transcript variants have been found for this gene, but the full-length nature and/or biological validity of some variants have not been determined. Mutations in this gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseus heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors.
  • Cellular localization

    Cell Membrane
  • Database links

  • Alternative names

    • Adenylate cyclase stimulating G alpha protein antibody
    • AHO antibody
    • Alternative gene product encoded by XL exon antibody
    • C20orf45 antibody
    • dJ309F20.1.1 antibody
    • dJ806M20.3.3 antibody
    • Extra large alphas protein antibody
    • GNAS antibody
    • GNAS complex locus antibody
    • GNAS1 antibody
    • GPSA antibody
    • Gs alpha subunit antibody
    • GSA antibody
    • GSP antibody
    • Guanine nucleotide binding protein (G protein) alpha stimulating activity polypeptide 1 antibody
    • Guanine nucleotide binding protein alpha stimulating activity polypeptide 1 antibody
    • Guanine nucleotide binding protein G(s) subunit alpha isoforms short antibody
    • Guanine nucleotide binding protein G(s) subunit alpha isoforms XLas antibody
    • Guanine nucleotide regulatory protein antibody
    • MGC33735 antibody
    • NESP antibody
    • NESP55 antibody
    • Neuroendocrine secretory protein antibody
    • PHP1A antibody
    • PHP1B antibody
    • PHP1C antibody
    • POH antibody
    • Protein ALEX antibody
    • Protein GNAS antibody
    • Protein NESP55 antibody
    • SCG6 antibody
    • Secretogranin VI antibody
    • XLalphas antibody
    • XLas antibody
    see all

Images

  • All lanes : Anti-G protein alpha S antibody (ab97629) at 1/1000 dilution

    Lane 1 : HepG2 whole cell lysate
    Lane 2 : Raji whole cell lysate

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 46 kDa



    10% SDS PAGE

References

This product has been referenced in:

  • Ishida Y  et al. Candida albicans ß-Glucan-Containing Particles Increase HO-1 Expression in Oral Keratinocytes via a Reactive Oxygen Species/p38 Mitogen-Activated Protein Kinase/Nrf2 Pathway. Infect Immun 86:N/A (2018). Read more (PubMed: 29311246) »
See 1 Publication for this product

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