Overview

  • Product name

    G3335, PPARgamma antagonist.
  • Description

    Selective, cell-permeable, reversible PPARγ antagonist.
  • Biological description

    Selective, cell-permeable, reversible PPARγ antagonist (Kd = 8 μM). Inhibits activity of PPARγ agonist Rosiglitazone (ab120762). Active in vivo.
  • Purity

    > 97%
  • CAS Number

    36099-95-3
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Meng QQ  et al. Rosiglitazone enhances the proliferation of neural progenitor cells and inhibits inflammation response after spinal cord injury. Neurosci Lett 503:191-5 (2011). Read more (PubMed: 21889575) »
  • Mettu NB  et al. The nuclear receptor-coactivator interaction surface as a target for peptide antagonists of the peroxisome proliferator-activated receptors. Mol Endocrinol 21:2361-77 (2007). Read more (PubMed: 17595321) »
  • Ye F  et al. The dipeptide H-Trp-Glu-OH shows highly antagonistic activity against PPARgamma: bioassay with molecular modeling simulation. Chembiochem 7:74-82 (2006). Read more (PubMed: 16317783) »
See all 2 Publications for this product

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