Overview

  • Product name

  • Description

    Rabbit polyclonal to G6PC3
  • Host species

    Rabbit
  • Tested applications

    Suitable for: ICC/IFmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human G6PC3 aa 76-107. ENSEMBL: ENSG00000141349
    Sequence:

    FGWVHESGYYSQAPAQVHQFPSSCETG


    Database link: Q9BUM1

  • Positive control

    • ICC/IF: PC-3 cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab221647 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 1 - 4 µg/ml.
Fixation/Permeabilization: PFA/Triton X-100.

 

Target

  • Relevance

    G6PC3 is the catalytic subunit of glucose-6-phosphatase (G6Pase). G6Pase is located in the endoplasmic reticulum (ER) and catalyzes the hydrolysis of glucose-6-phosphate to glucose and phosphate in the last step of the gluconeogenic and glycogenolytic pathways. Mutations in this gene result in autosomal recessive severe congenital neutropenia. Multiple transcript variants have been found for this gene, only one of which is expected to express a protein.
  • Cellular localization

    Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • Database links

  • Alternative names

    • G-6-Pase 3 antibody
    • G6Pase 3 antibody
    • G6Pase-beta antibody
    • Glucose 6 phosphatase, catalytic, 3 antibody
    • Glucose-6-phosphatase 3 antibody
    • Glucose-6-phosphatase beta antibody
    • SCN4 antibody
    • Ubiquitous glucose-6-phosphatase catalytic subunit-related protein antibody
    • UGRP antibody
    see all

Images

  • PFA-fixed, Triton X-100 permeabilized PC-3 (human prostate adenocarcinoma cell line) cells stained for G6PC3 (green) using ab221647 at 4 µg/ml in ICC/IF. 

     

References

ab221647 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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