Anti-GABA A Receptor alpha 2/GABRA2 antibody (ab153980)
Key features and details
- Rabbit polyclonal to GABA A Receptor alpha 2/GABRA2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-GABA A Receptor alpha 2/GABRA2 antibody
See all GABA A Receptor alpha 2/GABRA2 primary antibodies -
Description
Rabbit polyclonal to GABA A Receptor alpha 2/GABRA2 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Cow, Xenopus laevis -
Immunogen
Recombinant fragment corresponding to Human GABA A Receptor alpha 2/GABRA2 aa 1-330.
Database link: P47869 -
Positive control
- NT2D1 cell lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab153980 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB | (1) |
1/500 - 1/3000. Predicted molecular weight: 51 kDa.
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Notes |
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WB
1/500 - 1/3000. Predicted molecular weight: 51 kDa. |
Target
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Function
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. -
Sequence similarities
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA2 sub-subfamily. -
Cellular localization
Cell junction > synapse > postsynaptic cell membrane. Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 282236 Cow
- Entrez Gene: 2555 Human
- Entrez Gene: 14395 Mouse
- Entrez Gene: 289606 Rat
- Omim: 137140 Human
- SwissProt: P10063 Cow
- SwissProt: P47869 Human
- SwissProt: P26048 Mouse
see all -
Alternative names
- GABA A receptor subunit alpha 2 antibody
- GABA antibody
- GABA(A) receptor subunit alpha 2 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab153980 has been referenced in 1 publication.
- Huo J et al. ALG13 participates in epileptogenesis via regulation of GABAA receptors in mouse models. Cell Death Discov 6:87 (2020). PubMed: 33014431