Overview

  • Product name

    Anti-GABA A Receptor alpha 2/GABRA2 antibody
    See all GABA A Receptor alpha 2/GABRA2 primary antibodies
  • Description

    Rabbit polyclonal to GABA A Receptor alpha 2/GABRA2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WB, Flow Cytmore details
  • Species reactivity

    Reacts with: Mouse, Rat
    Predicted to work with: Human
  • Immunogen

    Synthetic peptide within Human GABA A Receptor alpha 2/GABRA2 aa 200-250 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Sequence:

    YNASDSVQVAP DGSRLNQYDL LGQSIGKETI KSSTGEYTVM TAHFHLKRKI


    Database link: P47869

  • Positive control

    • Rat brain tissue; Mouse brain cell lysate; RSC96 cells.
  • General notes

     This product was previously labelled as GABA A Receptor alpha 2

     

Properties

Applications

Our Abpromise guarantee covers the use of ab216973 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500.
WB 1/100 - 1/1000. Predicted molecular weight: 51 kDa.
Flow Cyt 1/20 - 1/100.

Target

  • Function

    GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
  • Sequence similarities

    Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA2 sub-subfamily.
  • Cellular localization

    Cell junction > synapse > postsynaptic cell membrane. Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • GABA A receptor subunit alpha 2 antibody
    • GABA antibody
    • GABA(A) receptor subunit alpha 2 antibody
    • GABA(A) receptor subunit alpha-2 antibody
    • GABR A2 antibody
    • GABRA 2 antibody
    • GABRA2 antibody
    • GABRA2 protein antibody
    • Gamma aminobutyric acid (GABA) A receptor alpha 2 antibody
    • Gamma aminobutyric acid A receptor alpha 2 antibody
    • Gamma aminobutyric acid receptor alpha 2 subunit antibody
    • Gamma aminobutyric acid receptor subunit alpha 2 antibody
    • Gamma-aminobutyric acid receptor subunit alpha-2 antibody
    • GBRA2_HUMAN antibody
    see all

Images

  • Anti-GABA A Receptor alpha 2/GABRA2 antibody (ab216973) at 1/300 dilution + Mouse brain cell lysate

    Secondary
    conjugated secondary at 1/5000 dilution

    Predicted band size: 51 kDa

  • Flow Cytometric analysis of RSC96 cells labeling GABA A Receptor alpha 2/GABRA2 with ab216973 at 1/100 dilution followed by incubation with a conjugated secondary (PE Conjugated) (green) for 30 minutes compared to control cells (blue), secondary only (light blue) and isotype control (orange).

  • Immunohistochemical analysis of Formalin-fixed, paraffin-embedded Rat brain tissue labeling GABA A Receptor alpha 2/GABRA2 with ab216973 at 1/200 dilution followed by conjugation to the secondary antibody and DAB staining.

References

ab216973 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab216973.
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