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Neuroscience Neurotransmission Receptors / Channels Ligand-Gated Ion Channels GABA Receptors
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Anti-GABA A Receptor alpha 3/GABRA3 antibody (ab110917)

  • Datasheet
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GABA A Receptor alpha 3/GABRA3 antibody (ab110917)

    Key features and details

    • Goat polyclonal to GABA A Receptor alpha 3/GABRA3
    • Suitable for: IHC-P
    • Reacts with: Human
    • Isotype: IgG

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    Recombinant Human GABA A Receptor alpha 3/GABRA3 protein (ab152409)

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    Overview

    • Product name

      Anti-GABA A Receptor alpha 3/GABRA3 antibody
      See all GABA A Receptor alpha 3/GABRA3 primary antibodies
    • Description

      Goat polyclonal to GABA A Receptor alpha 3/GABRA3
    • Host species

      Goat
    • Tested Applications & Species

      Application Species
      IHC-P
      Human
      See all applications and species data
    • Immunogen

      Synthetic peptide corresponding to Human GABA A Receptor alpha 3/GABRA3 (C terminal) conjugated to keyhole limpet haemocyanin.

    • Positive control

      • Human brain cortex tissue.
    • General notes

       This product was previously labelled as GABA A Receptor alpha 3

       

    Properties

    • Form

      Liquid
    • Storage instructions

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
    • Storage buffer

      pH: 7.30
      Preservative: 0.02% Sodium azide
      Constituents: Tris buffered saline, 0.5% BSA
    • Concentration information loading...
    • Purity

      Protein G purified
    • Clonality

      Polyclonal
    • Isotype

      IgG
    • Research areas

      • Neuroscience
      • Neurotransmission
      • Receptors / Channels
      • Ligand-Gated Ion Channels
      • GABA Receptors

    Associated products

    • Compatible Secondaries

      • Donkey Anti-Goat IgG H&L (Alexa Fluor® 488) (ab150129)
      • Donkey Anti-Goat IgG H&L (HRP) (ab205723)
    • Isotype control

      • Goat IgG, polyclonal - Isotype Control (ab37373)
    • Recombinant Protein

      • Recombinant Human GABA A Receptor alpha 3/GABRA3 protein (ab152409)

    Applications

    The Abpromise guarantee

    Our Abpromise guarantee covers the use of ab110917 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Guaranteed

    Tested applications are guaranteed to work and covered by our Abpromise guarantee.

    Predicted

    Predicted to work for this combination of applications and species but not guaranteed.

    Incompatible

    Does not work for this combination of applications and species.

    Application Species
    IHC-P
    Human
    All applications
    Mouse
    Rat
    Cow
    Dog
    Application Abreviews Notes
    IHC-P
    Use a concentration of 2.5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
    Notes
    IHC-P
    Use a concentration of 2.5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

    Target

    • Function

      GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
    • Sequence similarities

      Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA3 sub-subfamily.
    • Cellular localization

      Cell junction > synapse > postsynaptic cell membrane. Cell membrane.
    • Target information above from: UniProt accession P34903 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links

      • Entrez Gene: 282237 Cow
      • Entrez Gene: 492223 Dog
      • Entrez Gene: 2556 Human
      • Entrez Gene: 14396 Mouse
      • Entrez Gene: 24947 Rat
      • Omim: 305660 Human
      • SwissProt: P10064 Cow
      • SwissProt: P34903 Human
      • SwissProt: P26049 Mouse
      • SwissProt: P20236 Rat
      • Unigene: 123024 Human
      • Unigene: 102286 Mouse
      • Unigene: 447666 Mouse
      • Unigene: 10367 Rat
      see all
    • Alternative names

      • GABA A Receptor alpha 3 antibody
      • GABA(A) receptor subunit alpha 3 antibody
      • GABA(A) receptor subunit alpha-3 antibody
      • GABR A3 antibody
      • GABRA 3 antibody
      • Gabra3 antibody
      • Gamma aminobutyric acid (GABA) A receptor alpha 3 antibody
      • Gamma aminobutyric acid A receptor alpha 3 antibody
      • Gamma aminobutyric acid receptor subunit alpha 3 antibody
      • Gamma-aminobutyric acid receptor subunit alpha-3 antibody
      • GBRA3_HUMAN antibody
      • MGC33793 antibody
      see all

    Images

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GABA A Receptor alpha 3/GABRA3 antibody (ab110917)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GABA A Receptor alpha 3/GABRA3 antibody (ab110917)

      ab110917, at 2.5 µg/ml, staining GABA A Receptor alpha 3/GABRA3 in formalin fixed, paraffin embedded Human brain cortex tissue by Immunohistochemistry. A biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen was used to develop staining.

    Protocols

    • Immunohistochemistry protocols

    Click here to view the general protocols

    Datasheets and documents

    • SDS download

    • Datasheet download

      Download

    References (0)

    Publishing research using ab110917? Please let us know so that we can cite the reference in this datasheet.

    ab110917 has not yet been referenced specifically in any publications.

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