Anti-GABA A Receptor alpha 3/GABRA3 antibody (ab110917)
- Datasheet
- References
- Protocols
Overview
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Product name
Anti-GABA A Receptor alpha 3/GABRA3 antibody
See all GABA A Receptor alpha 3/GABRA3 primary antibodies -
Description
Goat polyclonal to GABA A Receptor alpha 3/GABRA3 -
Host species
Goat -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Cow, Dog
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Immunogen
Synthetic peptide corresponding to Human GABA A Receptor alpha 3/GABRA3 (C terminal) conjugated to keyhole limpet haemocyanin.
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Positive control
- Human brain cortex tissue.
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General notes
This product was previously labelled as GABA A Receptor alpha 3
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
Storage buffer
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: Tris buffered saline, 0.5% BSA -
Concentration information loading... -
Purity
Protein G purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab110917 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P | Use a concentration of 2.5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
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Function
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. -
Sequence similarities
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA3 sub-subfamily. -
Cellular localization
Cell junction > synapse > postsynaptic cell membrane. Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 282237 Cow
- Entrez Gene: 492223 Dog
- Entrez Gene: 2556 Human
- Entrez Gene: 14396 Mouse
- Entrez Gene: 24947 Rat
- Omim: 305660 Human
- SwissProt: P10064 Cow
- SwissProt: P34903 Human
see all -
Alternative names
- GABA A Receptor alpha 3 antibody
- GABA(A) receptor subunit alpha 3 antibody
- GABA(A) receptor subunit alpha-3 antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GABA A Receptor alpha 3/GABRA3 antibody (ab110917)ab110917, at 2.5 µg/ml, staining GABA A Receptor alpha 3/GABRA3 in formalin fixed, paraffin embedded Human brain cortex tissue by Immunohistochemistry. A biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen was used to develop staining.
Protocols
Datasheets and documents
References
ab110917 has not yet been referenced specifically in any publications.
