Product nameAnti-GABA A Receptor beta 1 antibody
See all GABA A Receptor beta 1 primary antibodies
DescriptionRabbit polyclonal to GABA A Receptor beta 1
SpecificityReacts with the 51-54 kDa beta 1 subunit of rat brain GABA A. There is no homology or known reactivity with other GABA subunits.
Tested applicationsSuitable for: IHC-P, WB, IPmore details
Species reactivityReacts with: Mouse, Rat, Human
Fusion protein of MBP with the amino acid sequence representing the cytosolic loop of the rat GABA A receptor beta 1 subunit.
- rat forebrain lysate, rat cerebellum or cortex lysate
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferpH: 7.50
Constituents: 0.238% HEPES, 50% Glycerol, 0.87% Sodium chloride, 0.01% BSA
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab16703 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use at an assay dependent concentration. PubMed: 18539546|
|WB||1/1000. Predicted molecular weight: 53 kDa.|
|IP||Use at an assay dependent concentration. Use at an assay dependent dilution. 15 ug of antibody were used to IP 24% of all GABA-A receptors in dodecylsulfate extracts of rat forebrains (150 ul).|
FunctionGABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
Sequence similaritiesBelongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRB1 sub-subfamily.
Cellular localizationCell junction > synapse > postsynaptic cell membrane. Cell membrane.
- Information by UniProt
- AW061132 antibody
- B230208N19Rik antibody
- GABA(A) receptor beta 1 antibody
All lanes : Anti-GABA A Receptor beta 1 antibody (ab16703) at 1/1000 dilution
Lane 1 : Cerebellum lysate
Lane 2 : Cortex lysate
Predicted band size: 53 kDa
Observed band size: 51 kDa why is the actual band size different from the predicted?
This product has been referenced in:
- Quintana A et al. Lack of GPR88 enhances medium spiny neuron activity and alters motor- and cue-dependent behaviors. Nat Neurosci 15:1547-55 (2012). Mouse . Read more (PubMed: 23064379) »
- Adusei DC et al. Early developmental alterations in GABAergic protein expression in fragile X knockout mice. Neuropharmacology 59:167-71 (2010). WB ; Mouse . Read more (PubMed: 20470805) »