Gabamide Hydrochloride (4-aminobutanamide hydrochloride), GABA uptake inhibitor (ab144683)

Overview

  • Product name

    Gabamide Hydrochloride (4-aminobutanamide hydrochloride), GABA uptake inhibitor
  • Description

    GABA uptake inhibitor
  • Alternative names

    • 4-aminobutanamide hydrochloride
  • Biological description

    GABA uptake inhibitor. Spider web component. Putative reversible EGFR inhibitor.
  • CAS Number

    13031-62-4
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    4-Aminobutyramide hydrochloride
  • Molecular weight

    138.60
  • Molecular formula

    C4H10N2O.HCl
  • PubChem identifier

    3014709
  • Storage instructions

    Store at Room Temperature. Store In the Dark. This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes.
  • Solubility overview

    Soluble in water
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C(CC(=O)N)CN.Cl
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Kowalczyk P  et al. Synthesis, biological evaluation and structure-activity relationship of new GABA uptake inhibitors, derivatives of 4-aminobutanamides. Eur J Med Chem 83:256-73 (2014). Read more (PubMed: 24973660) »
  • Townley MA  et al. Small organic solutes in sticky droplets from orb webs of the spider Zygiella atrica (Araneae; Araneidae): ß-alaninamide is a novel and abundant component. Chem Biodivers 9:2159-74 (2012). Read more (PubMed: 23081916) »
  • Townley MA  et al. Changes in composition of spider orb web sticky droplets with starvation and web removal, and synthesis of sticky droplet compounds. J Exp Biol 209:1463-86 (2006). Read more (PubMed: 16574806) »

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