Gaboxadol hydrochloride (THIP hydrochloride), GABAA receptor agonist and GABAC receptor antagonist (ab120426)

Overview

  • Product name

    Gaboxadol hydrochloride (THIP hydrochloride), GABAA receptor agonist and GABAC receptor antagonist
  • Description

    GABAA receptor agonist and GABAC receptor antagonist
  • Biological description

    GABAA receptor agonist and GABAC receptor antagonist. Antinociceptive, anticonvulsant and hypnotic agent. Blood-brain barrier permeable. Active in vivo and in vitro.
  • Purity

    > 98%
  • CAS Number

    64603-91-4
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Morishita W & Sastry BR Postsynaptic mechanisms underlying long-term depression of GABAergic transmission in neurons of the deep cerebellar nuclei. J Neurophysiol 76:59-68 (1996). Read more (PubMed: 8836209) »
  • Johnston GA GABAc receptors: relatively simple transmitter -gated ion channels? Trends Pharmacol Sci 17:319-23 (1996). Read more (PubMed: 8885697) »
  • Krogsgaard-Larsen P  et al. 4,5,6,7-Tetrahydroisothiazolo[5,4-c]pyridin-3-ol and related analogues of THIP. Synthesis and biological activity. J Med Chem 26:895-900 (1983). Read more (PubMed: 6304315) »
See 1 Publication for this product

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab120426.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
For licensing inquiries, please contact partnerships@abcam.com

Sign up