Key features and details
- Rabbit polyclonal to GABRB1
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-GABRB1 antibody
See all GABRB1 primary antibodies
DescriptionRabbit polyclonal to GABRB1
SpecificityReacts with the 51-54 kDa beta 1 subunit of rat brain GABA A. There is no homology or known reactivity with other GABA subunits.
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Mouse, Rat, Human
Synthetic peptide corresponding to Rat GABRB1.
- rat forebrain lysate, rat cerebellum or cortex lysate
This product was previously labelled as GABA A Receptor beta 1
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferpH: 7.50
Constituents: 0.238% HEPES, 50% Glycerol, 0.87% Sodium chloride, 0.01% BSA
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab16703 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000. Predicted molecular weight: 53 kDa.|
FunctionGABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
Sequence similaritiesBelongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRB1 sub-subfamily.
Cellular localizationCell junction > synapse > postsynaptic cell membrane. Cell membrane.
- Information by UniProt
- AW061132 antibody
- B230208N19Rik antibody
- GABA(A) receptor beta 1 antibody
All lanes : Anti-GABRB1 antibody (ab16703) at 1/1000 dilution
Lane 1 : Cerebellum lysate
Lane 2 : Cortex lysate
Predicted band size: 53 kDa
Observed band size: 51 kDa why is the actual band size different from the predicted?
ab16703 has been referenced in 3 publications.
- Quintana A et al. Lack of GPR88 enhances medium spiny neuron activity and alters motor- and cue-dependent behaviors. Nat Neurosci 15:1547-55 (2012). Mouse . PubMed: 23064379
- Adusei DC et al. Early developmental alterations in GABAergic protein expression in fragile X knockout mice. Neuropharmacology 59:167-71 (2010). WB ; Mouse . PubMed: 20470805
- Jin N et al. Ionotropic GABA receptor expression in the lung during development. Gene Expr Patterns 8:397-403 (2008). WB, IHC-P ; Rat . PubMed: 18539546