Overview

  • Product name

    Anti-GABRB1 antibody [EPR10343]
    See all GABRB1 primary antibodies
  • Description

    Rabbit monoclonal [EPR10343] to GABRB1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: ICC/IF,IHC-P or IP
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    corresponding to Human GABRB1 (internal sequence).
    Database link: P18505

  • Positive control

    • Human cerebellum and fetal brain tissue lysates.
  • General notes

     

     

     This product was previously labelled as GABA A Receptor beta 1

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab154822 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 54 kDa.
  • Application notes
    Is unsuitable for ICC/IF,IHC-P or IP.
  • Target

    • Function

      GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
    • Sequence similarities

      Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRB1 sub-subfamily.
    • Cellular localization

      Cell junction > synapse > postsynaptic cell membrane. Cell membrane.
    • Information by UniProt
    • Database links

    • Alternative names

      • AW061132 antibody
      • B230208N19Rik antibody
      • GABA(A) receptor beta 1 antibody
      • GABA(A) receptor subunit beta-1 antibody
      • GABA-A receptor, beta-1 polypeptide antibody
      • Gabrb-1 antibody
      • GABRB1 antibody
      • Gamma aminobutyric acid (GABA) A receptor beta 1 antibody
      • Gamma Aminobutyric Acid A Receptor Beta 1 antibody
      • Gamma Aminobutyric Acid Receptor , beta-1 antibody
      • Gamma-aminobutyric acid (GABA) A receptor, subunit beta 1 antibody
      • Gamma-aminobutyric acid receptor subunit beta-1 antibody
      • GARB1 antibody
      • GBRB1_HUMAN antibody
      see all

    Images

    • All lanes : Anti-GABRB1 antibody [EPR10343] (ab154822) at 1/1000 dilution

      Lane 1 : Human cerebellum tissue lysate
      Lane 2 : Human fetal brain tissue lysate

      Lysates/proteins at 10 µg per lane.

      Predicted band size: 54 kDa

    References

    This product has been referenced in:

    • Kaneko Y  et al. Oxytocin modulates GABAAR subunits to confer neuroprotection in stroke in vitro. Sci Rep 6:35659 (2016). WB ; Rat . Read more (PubMed: 27767042) »
    • Pan B  et al. Chronic administration of aripiprazole activates GSK3ß-dependent signalling pathways, and up-regulates GABAA receptor expression and CREB1 activity in rats. Sci Rep 6:30040 (2016). WB ; Rat . Read more (PubMed: 27435909) »
    See all 2 Publications for this product

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab154822.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

    Sign up