Product nameAnti-GABRE antibody [S413-67]
See all GABRE primary antibodies
DescriptionMouse monoclonal [S413-67] to GABRE
Tested applicationsSuitable for: WB, ICC/IFmore details
Species reactivityReacts with: Rat, Human
Fusion protein corresponding to Human GABRE aa 27-253. Extracellular N-terminus
SKNEASSRDVVYGPQPQPLENQLLSEETKSTETETGSRVGKLPEASRILN TILSNYDHKLRPGIGEKPTVVTVEISVNSLGPLSILDMEYTIDIIFSQTW YDERLCYNDTFESLVLNGNVVSQLWIPDTFFRNSKRTHEHEITMPNQMVR IYKDGKVLYTIRMTIDAGCSLHMLRFPMDSHSCPLSFSSFSYPENEMIYK WENFKLEINEKNSWKLFQFDFTGVSNK
Database link: P78334
- WB: Rat brain tissue lysate. ICC/IF: SK-N-BE cells.
This product was previously labelled as GABA Receptor Epsilon
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Preservative: 0.1% Sodium azide
Constituents: PBS, 50% Glycerol
Concentration information loading...
PurityProtein G purified
Our Abpromise guarantee covers the use of ab241998 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000. Predicted molecular weight: 58 kDa.|
FunctionGABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
Tissue specificityExpressed in many tissues. Highest levels of expression in adult heart and placenta.
Sequence similaritiesBelongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRE sub-subfamily.
Cellular localizationCell junction > synapse > postsynaptic cell membrane. Cell membrane.
- Information by UniProt
- GABA(A) receptor epsilon antibody
- GABA(A) receptor subunit epsilon antibody
- Gabre antibody
4% formaldehyde-fixed SK-N-BE (human neuroblastoma cell line) cells stained for GABRE (green, C) using ab241998 at 1/100 dilution for 1 hour at room temperature in ICC/IF. Secondary antibody is Goat Anti-Mouse ATTO 488 at 1/100 dilution. Actin is detected with Phalloidin Texas Red F-Actin stain (red, B). The nuclear counterstain is DAPI (blue, A). (D) is a composite image.
Anti-GABRE antibody [S413-67] (ab241998) at 1/1000 dilution + Rat brain tissue lysate at 10 µg
Goat Anti-Mouse IgG: HRP at 1/200 dilution
Developed using the ECL technique.
Predicted band size: 58 kDa
Exposure time: 6 minutes
Primary and secondary incubation for 1 hour at room temperature.
Blocked for 1 hr at RT.
ab241998 has not yet been referenced specifically in any publications.