Product nameGABRP peptide
Our Abpromise guarantee covers the use of ab206287 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at -20°C.
ReconstitutionReconstitute with 100ul of sterile PBS.
- GABA(A) receptor subunit pi
- Gamma aminobutyric acid (GABA) A receptor pi
FunctionGABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. In the uterus, the function of the receptor appears to be related to tissue contractility. The binding of this pI subunit with other GABA(A) receptor subunits alters the sensitivity of recombinant receptors to modulatory agents such as pregnanolone.
Tissue specificityMost abundant in the uterus, also expressed in lung, thymus and prostate.
Sequence similaritiesBelongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRP sub-subfamily.
Cellular localizationCell junction > synapse > postsynaptic cell membrane. Cell membrane.
- Information by UniProt
ab206287 has not yet been referenced specifically in any publications.