Product nameAnti-GABRQ antibody
DescriptionRabbit polyclonal to GABRQ
SpecificityThis antibody recognizes GABRQ
Tested applicationsSuitable for: ELISA, WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat, Cow, Dog
- Jurkat cell lysate
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferPreservative: 0.09% Sodium azide
Constituents: 2% Sucrose, PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab49188 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ELISA||Use at an assay dependent concentration.
Titre using peptide based assay was 1/12500.
|WB||Use a concentration of 0.25 µg/ml. Detects a band of approximately 70 kDa (predicted molecular weight: 72 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.|
RelevanceThe gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, theta subunit. GABRQ gene is mapped to chromosome Xq28 in a cluster including the genes encoding the alpha 3 and epsilon subunits of the same receptor. This gene location is also the candidate region of 2 different neurologic diseases: early-onset parkinsonism (Waisman syndrome) and X linked mental retardation (MRX3).
Cellular localizationCell Membrane
- gamma aminobutyric acid (GABA) receptor, theta antibody
- Gamma aminobutyric acid receptor theta subunit precursor antibody
- gamma aminobutyric acid receptor, theta antibody
- THETA antibody
Lane 1 : Marker
Lane 2 : Anti-GABRQ antibody (ab49188) at 0.25 µg/ml
Lane 2 : Jurkat cell lysate at 10 µg with 5% skim milk in PBS.
Lane 2 : HRP conjugated anti-Rabbit IgG at 1/50000 dilution
Predicted band size: 72 kDa
Observed band size: 70 kDa why is the actual band size different from the predicted?
Gel concentration: 12%
This product has been referenced in:
- Fatemi SH et al. mRNA and protein expression for novel GABAA receptors ? and ?2 are altered in schizophrenia and mood disorders; relevance to FMRP-mGluR5 signaling pathway. Transl Psychiatry 3:e271 (2013). WB ; Human . Read more (PubMed: 23778581) »