Anti-GABRR1 antibody (ab189875)
Key features and details
- Rabbit polyclonal to GABRR1
- Suitable for: WB
- Reacts with: Mouse, Human
- Isotype: IgG
Overview
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Product name
Anti-GABRR1 antibody -
Description
Rabbit polyclonal to GABRR1 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse, Human -
Immunogen
Recombinant fragment corresponding to Human GABRR1 aa 350 to the C-terminus.
Database link: P24046 -
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol, 49% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab189875 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/2000. Predicted molecular weight: 56 kDa.
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Notes |
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WB
1/500 - 1/2000. Predicted molecular weight: 56 kDa. |
Target
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Function
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-1 GABA receptor could play a role in retinal neurotransmission. -
Tissue specificity
Highly expressed in the retina and in a lesser extent in brain, lung and thymus. -
Sequence similarities
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRR1 sub-subfamily. -
Cellular localization
Cell junction > synapse > postsynaptic cell membrane. Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 2569 Human
- Entrez Gene: 14408 Mouse
- Omim: 137161 Human
- SwissProt: P24046 Human
- SwissProt: P56475 Mouse
- Unigene: 99927 Human
- Unigene: 14116 Mouse
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Alternative names
- bA135P14.1 (gamma-aminobutyric acid (GABA) receptor rho 1) antibody
- GABA(A) receptor subunit rho-1 antibody
- GABA(C) receptor antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab189875 has not yet been referenced specifically in any publications.