Recombinant
RabMAb

Anti-GAD67 antibody [EPR2550] (ab108626)

Overview

  • Product name
    Anti-GAD67 antibody [EPR2550]
    See all GAD67 primary antibodies
  • Description
    Rabbit monoclonal [EPR2550] to GAD67
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IPmore details
    Unsuitable for: Flow Cyt,ICC or IHC-P
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human GAD67 aa 50-150. The exact sequence is proprietary.

  • Positive control
    • Human fetal brain, SH-SY5Y, Human fetal hypothalamus, Jurkat, C6, and Neuro2a cell lysates.
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    We are constantly working hard to ensure we provide our customers with best in class antibodies. As a result of this work we are pleased to now offer this antibody in purified format. We are in the process of updating our datasheets. The purified format is designated 'PUR' on our product labels. If you have any questions regarding this update, please contact our Scientific Support team.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab108626 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 67 kDa.
IP 1/10 - 1/100.
  • Application notes
    Is unsuitable for Flow Cyt,ICC or IHC-P.
  • Target

    • Function
      Catalyzes the production of GABA.
    • Tissue specificity
      Isoform 3 is expressed in pancreatic islets, testis, adrenal cortex, and perhaps other endocrine tissues, but not in brain.
    • Involvement in disease
      Defects in GAD1 are the cause of cerebral palsy spastic quadriplegic type 1 (CPSQ1) [MIM:603513]. A non-progressive disorder of movement and/or posture resulting from defects in the developing central nervous system. Affected individuals manifest symmetrical, non-progressive spasticity and no adverse perinatal history or obvious underlying alternative diagnosis. Developmental delay, mental retardation and sometimes epilepsy can be part of the clinical picture.
    • Sequence similarities
      Belongs to the group II decarboxylase family.
    • Information by UniProt
    • Database links
    • Alternative names
      • 67 kDa glutamic acid decarboxylase antibody
      • CPSQ1 antibody
      • DCE1 antibody
      • DCE1_HUMAN antibody
      • EC 4.1.1.15 antibody
      • FLJ45882 antibody
      • GAD 67 antibody
      • GAD antibody
      • GAD-67 antibody
      • GAD1 antibody
      • Glutamate decarboxylase 1 (brain, 67kDa) antibody
      • Glutamate decarboxylase 1 antibody
      • Glutamate decarboxylase 1 brain 67kD antibody
      • Glutamate decarboxylase 1 brain 67kDa antibody
      • Glutamate decarboxylase 67 kDa isoform antibody
      • Glutamate decarboxylase, brain, 67-KD antibody
      • OTTHUMP00000041055 antibody
      • SCP antibody
      see all

    Images

    • All lanes : Anti-GAD67 antibody [EPR2550] (ab108626) at 1/1000 dilution

      Lane 1 : Human fetal brain cell lysate
      Lane 2 : SH-SY5Y cell lysate
      Lane 3 : Human fetal hypothalamus cell lysate
      Lane 4 : Jurkat cell lysate
      Lane 5 : C6 cell lysate
      Lane 6 : Neuro2a cell lysate

      Lysates/proteins at 10 µg per lane.

      Predicted band size: 67 kDa

    References

    ab108626 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    Our tests indicate that ab108626 anti-GAD67 is unsuitable for immunostaining mouse tissue and cultured cells, but it is effective for staining western blots.

    Antibody ab26116 will be a better choice.
    Here is the URL of the datasheet. http...

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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