Anti-GADD45A antibody (ab180768)
Key features and details
- Rabbit polyclonal to GADD45A
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
Overview
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Product name
Anti-GADD45A antibody
See all GADD45A primary antibodies -
Description
Rabbit polyclonal to GADD45A -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse
Predicted to work with: Cow, Cat, Chinese hamster -
Immunogen
Recombinant full length protein corresponding to Human GADD45A aa 1-165.
Sequence:MTLEEFSAGE QKTERMDKVG DALEEVLSKA LSQRTITVGV YEAAKLLNVD PDNVVLCLLA ADEDDDRDVA LQIHFTLIQA FCCENDINIL RVSNPGRLAE LLLLETDAGP AASEGAEQPP DLHCVLVTNP HSSQWKDPAL SQLICFCRES RYMDQWVPVI NLPERLE
Database link: P24522 -
Positive control
- WB: Mouse liver tissue lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
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Related Products
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab180768 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB | (1) |
1/500 - 1/2000. Predicted molecular weight: 18 kDa.
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Notes |
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WB
1/500 - 1/2000. Predicted molecular weight: 18 kDa. |
Target
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Function
Binds to proliferating cell nuclear antigen. Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase. -
Sequence similarities
Belongs to the GADD45 family. - Information by UniProt
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Database links
- Entrez Gene: 493656 Cat
- Entrez Gene: 505463 Cow
- Entrez Gene: 13197 Mouse
- SwissProt: Q60GI5 Cat
- SwissProt: P24523 Chinese hamster
- SwissProt: Q3ZBN6 Cow
- SwissProt: P48316 Mouse
- Unigene: 72235 Mouse
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Alternative names
- DDIT 1 antibody
- DDIT-1 antibody
- DDIT1 antibody
see all
Images
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (20)
ab180768 has been referenced in 20 publications.
- Peng C et al. Function of DHX33 in promoting Warburg effect via regulation of glycolytic genes. J Cell Physiol 236:981-996 (2021). PubMed: 32617965
- Yang Y & Shang H Silencing lncRNA-DGCR5 increased trophoblast cell migration, invasion and tube formation, and inhibited cell apoptosis via targeting miR-454-3p/GADD45A axis. Mol Cell Biochem 476:3407-3421 (2021). PubMed: 33973132
- Yang C et al. Circular RNA RBPMS inhibits bladder cancer progression via miR-330-3p/RAI2 regulation. Mol Ther Nucleic Acids 23:872-886 (2021). PubMed: 33614236
- Zhang YL et al. Progesterone suppresses the progression of colonic carcinoma by increasing the activity of the GADD45a/JNK/c-Jun signalling pathway. Oncol Rep 45:N/A (2021). PubMed: 33846816
- Zhao N et al. Androgen Receptor, Although Not a Specific Marker For, Is a Novel Target to Suppress Glioma Stem Cells as a Therapeutic Strategy for Glioblastoma. Front Oncol 11:616625 (2021). PubMed: 34094902