Overview

  • Product name

  • Description

    Rabbit polyclonal to GADD45B
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Cow
  • Immunogen

    Recombinant full length protein corresponding to Human GADD45B aa 1-160. BC113466.
    Sequence:

    MTLEELVACDNAAQKMQTVTAAVEELLVAAQRQDRLTVGVYESAKLMNVD PDSVVLCLLAIDEEEEDDIALQIHFTLIQSFCCDNDINIVRVSGMQRLAQ LLGEPAETQGTTEARDLHCLLVTNPHTDAWKSHGLVEVASYCEESRGNNQ WVPYISLQER


    Database link: O75293

  • Positive control

    • HeLa cell lysate; Human fetal heart tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab205252 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500.
WB 1/200 - 1/1000. Predicted molecular weight: 18 kDa.

Target

  • Function

    Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK.
  • Sequence similarities

    Belongs to the GADD45 family.
  • Information by UniProt
  • Database links

  • Form

    It localizes to the nucleus.
  • Alternative names

    • GA45B_HUMAN antibody
    • GADD45 Beta antibody
    • Gadd45b antibody
    • GADD45BETA antibody
    • Growth arrest and DNA damage inducible 45 beta antibody
    • Growth arrest and DNA damage inducible beta antibody
    • Growth arrest and DNA damage-inducible gene GADD45, beta antibody
    • Growth arrest and DNA damage-inducible protein GADD45 beta antibody
    • Growth arrest and DNA-damage-inducible protein GADD45 beta antibody
    • MY118 antibody
    • MYD118 antibody
    • MYD118, mouse, homolog of antibody
    • Myeloid differentiation primary response gene antibody
    • Myeloid differentiation primary response protein MyD118 antibody
    • Negative growth regulatory protein MyD118 antibody
    • Negative growth-regulatory protein MyD118 antibody
    see all

Images

  • Anti-GADD45B antibody (ab205252) at 1/500 dilution + HeLa cell lysate

    Predicted band size: 18 kDa

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded, Human fetal heart tissue labeling GADD45B with ab205252 at 1/100 dilution.

References

ab205252 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Application
Immunohistochemistry (Frozen sections)
Sample
Mouse Tissue sections (Tumor)
Permeabilization
No
Specification
Tumor
Blocking step
Serum as blocking agent for 30 minute(s) · Concentration: 1% · Temperature: 25°C
Fixative
Acetone

Abcam user community

Verified customer

Submitted Jun 01 2016

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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