Overview

  • Product name

    Anti-GADD45B antibody - C-terminal
    See all GADD45B primary antibodies
  • Description

    Rabbit polyclonal to GADD45B - C-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
    Predicted to work with: Cow, Monkey
  • Immunogen

    Synthetic peptide corresponding to Human GADD45B (C terminal) conjugated to keyhole limpet haemocyanin.
    Database link: O75293

  • Positive control

    • IHC-P: Human testis tissue. WB: MCF7, NIH/3T3 and H9c2 whole cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab230646 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 18 kDa.
IHC-P 1/100.

Target

  • Function

    Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK.
  • Sequence similarities

    Belongs to the GADD45 family.
  • Information by UniProt
  • Database links

  • Form

    It localizes to the nucleus.
  • Alternative names

    • GA45B_HUMAN antibody
    • GADD45 Beta antibody
    • Gadd45b antibody
    • GADD45BETA antibody
    • Growth arrest and DNA damage inducible 45 beta antibody
    • Growth arrest and DNA damage inducible beta antibody
    • Growth arrest and DNA damage-inducible gene GADD45, beta antibody
    • Growth arrest and DNA damage-inducible protein GADD45 beta antibody
    • Growth arrest and DNA-damage-inducible protein GADD45 beta antibody
    • MY118 antibody
    • MYD118 antibody
    • MYD118, mouse, homolog of antibody
    • Myeloid differentiation primary response gene antibody
    • Myeloid differentiation primary response protein MyD118 antibody
    • Negative growth regulatory protein MyD118 antibody
    • Negative growth-regulatory protein MyD118 antibody
    see all

Images

  • All lanes : Anti-GADD45B antibody - C-terminal (ab230646) at 1/500 dilution

    Lane 1 : MCF7 (human breast adenocarcinoma cell line) whole cell lysate.
    Lane 2 : NIH/3T3 (mouse embryo fibroblast cell line) whole cell lysate.
    Lane 3 : H9c2 (rat heart myoblast cell line) whole cell lysate.

    Predicted band size: 18 kDa

  • Formalin-fixed, paraffin-embedded, human testis tissue stained for GADD45B using ab230646 at 1/100 dilution in immunohistochemical analysis.

References

ab230646 has not yet been referenced specifically in any publications.

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