Overview

  • Product name

  • Description

    Rabbit polyclonal to GADD45G/CR6
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, ICC/IF, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide corresponding to Human GADD45G/CR6 (internal sequence).
    Database link: O95257

  • Positive control

    • A549 cells, Human lung carcinoma tissue.
  • General notes

     This product was previously labelled as GADD45G

     

Properties

Applications

Our Abpromise guarantee covers the use of ab196774 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 17 kDa.
ICC/IF 1/100 - 1/500.
IHC-P 1/50 - 1/100.

Target

  • Function

    Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK.
  • Sequence similarities

    Belongs to the GADD45 family.
  • Information by UniProt
  • Database links

  • Alternative names

    • CR6 antibody
    • Cytokine responsive protein CR6 antibody
    • Cytokine-responsive protein CR6 antibody
    • DDIT-2 antibody
    • DDIT2 antibody
    • DNA damage-inducible transcript 2 protein antibody
    • GA45G_HUMAN antibody
    • Gadd45g antibody
    • Growth arrest and DNA damage inducible gamma antibody
    • Growth arrest and DNA damage-inducible protein GADD45 gamma antibody
    • GRP17 antibody
    see all

Images

  • Immunohistochemical analysis of paraffin-embedded Human lung carcinoma tissue labeling GADD45G/CR6 with ab196774 at 1/50 dilution. The image on the right is treated with synthesized peptide.

  • Immunofluorescent analysis of A549 cells labelling GADD45G/CR6 with ab196774 at a 1/00 dilution. The image on the right is treated with synthesized peptide.

References

This product has been referenced in:

  • Sarmento-Cabral A  et al. Metformin Reduces Prostate Tumor Growth, in a Diet-Dependent Manner, by Modulating Multiple Signaling Pathways. Mol Cancer Res 15:862-874 (2017). Read more (PubMed: 28385910) »
  • Su X  et al. IL-27 attenuates airway inflammation in a mouse asthma model via the STAT1 and GADD45?/p38 MAPK pathways. J Transl Med 14:283 (2016). WB ; Mouse, Human . Read more (PubMed: 27687913) »
See all 2 Publications for this product

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab196774.
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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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