Overview

  • Product name

    Gadodiamide, MRI contrast agent
  • Description

    Non-ionic extracellular contrast agent for MRI
  • Biological description

    Non-ionic extracellular gadolinium-based contrast agent for MRI. Decreases both the T1 and T2 relaxation times. Blood-brain barrier permeable under pathological conditions only. Displays a short half-life in vivo.
  • Purity

    > 99%
  • CAS Number

    122795-43-1
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    2-[Bis[2-[carboxylatomethyl-[2-(methylamino)-2-oxoethyl]amino]ethyl]amino]acetate gadolinium(III) hydrate
  • Molecular weight

    591.67
  • Molecular formula

    C16H28GdN5O9
  • PubChem identifier

    60754
  • Storage instructions

    Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C(=O)(CN(CCN(CC(=O)[O-])CCN(CC([O-])=O)CC(NC)=O)CC(=O)[O-])NC.[Gd+3].O
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Bailey C  et al. Mapping water exchange rates in rat tumor xenografts using the late-stage uptake following bolus injections of contrast agent. Magn Reson Med 71:1874-87 (2014). Read more (PubMed: 23801522) »
  • Yip WL  et al. Classification of structurally related commercial contrast media by near infrared spectroscopy. J Pharm Biomed Anal 90:148-60 (2014). Read more (PubMed: 24374816) »
  • Harpur ES  et al. Preclinical safety assessment and pharmacokinetics of gadodiamide injection, a new magnetic resonance imaging contrast agent. Invest Radiol 28 Suppl 1:S28-43 (1993). Read more (PubMed: 8486501) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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