Key features and details
- Mouse polyclonal to Galactosidase alpha
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-Galactosidase alpha antibody
See all Galactosidase alpha primary antibodies
DescriptionMouse polyclonal to Galactosidase alpha
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
- Galactosidase alpha transfected 293T cell lysate.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Storage bufferpH: 7.4
Constituent: 100% PBS
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab169315 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 µg/ml. Predicted molecular weight: 49 kDa.|
Involvement in diseaseDefects in GLA are the cause of Fabry disease (FD) [MIM:301500]. FD is a rare X-linked sphingolipidosis disease where glycolipid accumulates in many tissues. The disease consists of an inborn error of glycosphingolipid catabolism. FD patients show systemic accumulation of globotriaoslyceramide (Gb3) and related glycosphingolipids in the plasma and cellular lysosomes throughout the body. Clinical recognition in males results from characteristic skin lesions (angiokeratomas) over the lower trunk. Patients may show ocular deposits, febrile episodes, and burning pain in the extremities. Death results from renal failure, cardiac or cerebral complications of hypertension or other vascular disease. Heterozygous females may exhibit the disorder in an attenuated form, they are more likely to show corneal opacities.
Sequence similaritiesBelongs to the glycosyl hydrolase 27 family.
- Information by UniProt
- AGAL_HUMAN antibody
- Agalsidase alfa antibody
- Alpha D galactosidase A antibody
All lanes : Anti-Galactosidase alpha antibody (ab169315) at 1 µg/ml
Lane 1 : Galactosidase alpha transfected 293T cell lysate
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 15 µl per lane.
All lanes : Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution
Developed using the ECL technique.
Predicted band size: 49 kDa
ab169315 has been referenced in 1 publication.
- Bohl C et al. Fluorescent probes for selective protein labeling in lysosomes: a case of a-galactosidase A. FASEB J 31:5258-5267 (2017). PubMed: 28821638