Key features and details
- Rabbit polyclonal to Galactoside 2-alpha-L-fucosyltransferase 1
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-Galactoside 2-alpha-L-fucosyltransferase 1 antibody
DescriptionRabbit polyclonal to Galactoside 2-alpha-L-fucosyltransferase 1
SpecificityDetects endogenous levels of total Galactoside 2-alpha-L-fucosyltransferase 1 protein.
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Human
Synthetic peptide corresponding to Human Galactoside 2-alpha-L-fucosyltransferase 1 (internal sequence).
Database link: P19526
- WB: Human cerebella and cerebrum tissue and Raji cell lysates; IHC: Human esophagus and cervical cancer tissue.
The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of a precursor of the H antigen, which is required for the final step in the soluble A and B antigen synthesis pathway. This gene is one of two encoding the galactoside 2-L-fucosyltransferase enzyme. Mutations in this gene are a cause of the H-Bombay blood group.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.4
Preservative: 0.05% Sodium azide
Constituents: 49% PBS, 50% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab198712 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/50 - 1/200.|
|WB||1/500 - 1/2000. Predicted molecular weight: 41 kDa.|
FunctionCreates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble A and B antigen synthesis pathway. H and Se enzymes fucosylate the same acceptor substrates but exhibit different Km values.
PathwayProtein modification; protein glycosylation.
Sequence similaritiesBelongs to the glycosyltransferase 11 family.
Cellular localizationGolgi apparatus > Golgi stack membrane. Membrane-bound form in trans cisternae of Golgi.
- Information by UniProt
- 2)FT 1 antibody
- 2-alpha-L-fucosyltransferase antibody
- Alpha (1 2) fucosyltransferase antibody
Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue using ab 198712 at dilution 1/35.
Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue using ab 198712 at dilution 1/35.
All lanes : Anti-Galactoside 2-alpha-L-fucosyltransferase 1 antibody (ab198712) at 1/800 dilution
Lane 1 : Human cerebella tissue
Lane 2 : Human cerebrum tissue
Lane 3 : Raji cell lysates
Lysates/proteins at 40 µg per lane.
All lanes : Goat anti rabbit IgG at 1/5000 dilution
Predicted band size: 41 kDa
Exposure time: 1 minute
ab198712 has not yet been referenced specifically in any publications.